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The Journal of Biological Chemistry|September 23, 2008
The TREX1 double-stranded DNA degradation activity is defective in dominant mutations associated with autoimmune diseaseDuane A Lehtinen, Scott Harvey, Matthew J Mulcahy, et al.
The Journal of Biological Chemistry|March 12, 2014
The Arg-62 residues of the TREX1 exonuclease act across the dimer interface contributing to catalysis in the opposing protomersJason M Fye, Stephanie R Coffin, Clinton D Orebaugh, et al.
The Journal of Biological Chemistry|August 3, 2011
Dominant mutation of the TREX1 exonuclease gene in lupus and Aicardi-Goutieres syndromeJason M Fye, Clinton D Orebaugh, Stephanie R Coffin, et al.
Nucleic Acids Research|May 2, 2006
The molecular mechanism of DNA damage recognition by MutS homologs and its consequences for cell death responseFreddie R Salsbury, Jill E Clodfelter, Michael B Gentry, et al.
DNA Repair|October 29, 2008
Small molecule induction of MSH2-dependent cell death suggests a vital role of mismatch repair proteins in cell deathAksana Vasilyeva, Jill E Clodfelter, Brian Rector, et al.
The Journal of Biological Chemistry|February 13, 2007
The crystal structure of TREX1 explains the 3' nucleotide specificity and reveals a polyproline II helix for protein partneringUdesh de Silva, Sumana Choudhury, Suzanna L Bailey, et al.
Scientific Reports|May 6, 2026
Scalable production of monovalent streptavidin with high yield and purityIan D Wadsworth, Komal Sethi, Sara Abu Jalboush, et al.
Plos Pathogens|April 19, 2012
The transcription factor AmrZ utilizes multiple DNA binding modes to recognize activator and repressor sequences of Pseudomonas aeruginosa virulence genesEdward E Pryor, Elizabeth A Waligora, Binjie Xu, et al.
The Journal of Biological Chemistry|June 7, 2008
Cooperative DNA binding and communication across the dimer interface in the TREX2 3' --> 5'-exonucleaseFred W Perrino, Udesh de Silva, Scott Harvey, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 8, 2015
Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory diseaseJessica L Grieves, Jason M Fye, Scott Harvey, et al.
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