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Nature Communications|June 1, 2024
Highly biased agonism for GPCR ligands via nanobody tetheringShivani Sachdev, Brendan A Creemer, Thomas J Gardella, et al.
Biorxiv : the Preprint Server for Biology|October 24, 2023
Highly biased agonism for GPCR ligands via nanobody tetheringShivani Sachdev, Brendan A Creemer, Thomas J Gardella, et al.
Cellular and Molecular Life Sciences : CMLS|August 13, 2010
Molecular basis of parathyroid hormone receptor signaling and trafficking: a family B GPCR paradigmJean-Pierre Vilardaga, Guillermo Romero, Peter A Friedman, et al.
Biochemistry|March 24, 2004
Cooperative interaction of arginine-19 and the N-terminal signaling domain in the affinity and potency of parathyroid hormoneNatia Tsomaia, Masaru Shimizu, Naoto Shimizu, et al.
RSC Chemical Biology|January 3, 2022
Activation of a G protein-coupled receptor through indirect antibody-mediated tethering of ligandsRoss W Cheloha, Fabian A Fischer, Thomas J Gardella, et al.
Endocrinology|November 13, 2015
Binding Selectivity of Abaloparatide for PTH-Type-1-Receptor Conformations and Effects on Downstream SignalingGary Hattersley, Thomas Dean, Braden A Corbin, et al.
The Journal of Biological Chemistry|August 23, 2006
Role of amino acid side chains in region 17-31 of parathyroid hormone (PTH) in binding to the PTH receptorThomas Dean, Ashok Khatri, Zhanna Potetinova, et al.
Nature Reviews. Endocrinology|August 26, 2015
PTH receptor-1 signalling-mechanistic insights and therapeutic prospectsRoss W Cheloha, Samuel H Gellman, Jean-Pierre Vilardaga, et al.
Trends in Pharmacological Sciences|June 20, 2012
Non-canonical signaling of the PTH receptorJean-Pierre Vilardaga, Thomas J Gardella, Vanessa L Wehbi, et al.
Biochemistry|January 21, 2004
Toward parathyroid hormone minimization: conformational studies of cyclic PTH(1-14) analoguesNatia Tsomaia, Maria Pellegrini, Kimberly Hyde, et al.
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