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Molecular Cancer Therapeutics|May 6, 2010
Schweinfurthin A selectively inhibits proliferation and Rho signaling in glioma and neurofibromatosis type 1 tumor cells in a NF1-GRD-dependent mannerThomas J Turbyville, Demirkan B Gürsel, Robert G Tuskan, et al.
Cytometry. Part a : the Journal of the International Society for Analytical Cytology|February 12, 2014
Quantitative analysis of F-actin redistribution in astrocytoma cells treated with candidate pharmaceuticalsStephen Lockett, Chrissie Verma, Alla Brafman, et al.
Journal of Natural Products|December 30, 2003
Cytotoxic constituents of Aspergillus terreus from the rhizosphere of Opuntia versicolor of the Sonoran DesertE M Kithsiri Wijeratne, Thomas J Turbyville, Zhongge Zhang, et al.
Journal of Natural Products|February 28, 2006
Search for Hsp90 inhibitors with potential anticancer activity: isolation and SAR studies of radicicol and monocillin I from two plant-associated fungi of the Sonoran desertThomas J Turbyville, E M Kithsiri Wijeratne, Manping X Liu, et al.
ACS Chemical Biology|August 14, 2023
Direct Modulators of K-Ras-Membrane InteractionsJohannes Morstein, Rebika Shrestha, Que N Van, et al.
Science Advances|July 14, 2023
RAS-dependent RAF-MAPK hyperactivation by pathogenic RIT1 is a therapeutic target in Noonan syndrome-associated cardiac hypertrophyAntonio Cuevas-Navarro, Morgan Wagner, Richard Van, et al.
The Journal of Biological Chemistry|May 13, 2020
RAS internal tandem duplication disrupts GTPase-activating protein (GAP) binding to activate oncogenic signalingAndrew C Nelson, Thomas J Turbyville, Srisathiyanarayanan Dharmaiah, et al.
Communications Biology|February 28, 2024
Membrane lipids drive formation of KRAS4b-RAF1 RBDCRD nanoclusters on the membraneRebika Shrestha, Timothy S Carpenter, Que N Van, et al.
Journal of Chemical Theory and Computation|July 22, 2022
Asynchronous Reciprocal Coupling of Martini 2.2 Coarse-Grained and CHARMM36 All-Atom Simulations in an Automated Multiscale FrameworkCesar A López, Xiaohua Zhang, Fikret Aydin, et al.
Proceedings of the National Academy of Sciences of the United States of America|September 15, 2025
An in vitro BRAF activation assay elucidates molecular mechanisms driving disassembly of the autoinhibited BRAF stateDaniel A Ritt, David E Durrant, Matthew R Drew, et al.
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