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Clinical Pharmacology and Therapeutics|May 7, 2026
A Review of Virtual Twins in Physiologically-Based Pharmacokinetic Modeling and SimulationEmily Mannix, Sam Mostafa, Amin Rostami-Hodjegan, et al.
Therapeutic Advances in Drug Safety|December 20, 2019
Precision dosing to avoid adverse drug reactionsThomas M Polasek, Carl M J Kirkpatrick, Amin Rostami-Hodjegan
CPT: Pharmacometrics & Systems Pharmacology|November 25, 2022
Delineating gene-environment effects using virtual twins of patients treated with clozapineSam Mostafa, Thomas M Polasek, Chad Bousman, et al.
CPT: Pharmacometrics & Systems Pharmacology|January 20, 2024
Virtual twins for model-informed precision dosing of clozapine in patients with treatment-resistant schizophreniaSam Mostafa, Reza Rafizadeh, Thomas M Polasek, et al.
Pharmacogenomics|September 28, 2022
Pharmacogenomics in psychiatry - the challenge of cytochrome P450 enzyme phenoconversion and solutions to assist precision dosingSam Mostafa, Thomas M Polasek, Chad A Bousman, et al.
Frontiers in Digital Health|October 2, 2023
Virtual twin for healthcare managementThomas M Polasek
Expert Review of Clinical Pharmacology|February 2, 2024
Pharmacogenomics - a minor rather than major force in clinical medicineThomas M Polasek
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