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Cancer Cell|March 16, 2017
ETO2-GLIS2 Hijacks Transcriptional Complexes to Drive Cellular Identity and Self-Renewal in Pediatric Acute Megakaryoblastic LeukemiaCécile Thirant, Cathy Ignacimouttou, Cécile K Lopez, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|March 30, 2020
Constitutive Activation of RAS/MAPK Pathway Cooperates with Trisomy 21 and Is Therapeutically Exploitable in Down Syndrome B-cell LeukemiaAnouchka P Laurent, Aurélie Siret, Cathy Ignacimouttou, et al.
The Journal of Experimental Medicine|October 10, 2012
Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft modelsClarisse Thiollier, Cécile K Lopez, Bastien Gerby, et al.
Cancer Cell|April 20, 2005
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosisRoss L Levine, Martha Wadleigh, Jan Cools, et al.
Blood|December 10, 2024
Progressive chromatin rewiring by ETO2::GLIS2 revealed in a genome-edited human iPSC model of pediatric leukemia initiationFabien Boudia, Marie Baille, Loélia Babin, et al.
Communications Biology|September 18, 2023
A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and refractory tumorsMaria Eugénia Marques Da Costa, Sakina Zaidi, Jean-Yves Scoazec, et al.
Cancer Discovery|April 26, 2019
A Recurrent Activating Missense Mutation in Waldenström Macroglobulinemia Affects the DNA Binding of the ETS Transcription Factor SPI1 and Enhances ProliferationDamien Roos-Weil, Camille Decaudin, Marine Armand, et al.
Cancer Discovery|October 31, 2019
Ontogenic Changes in Hematopoietic Hierarchy Determine Pediatric Specificity and Disease Phenotype in Fusion Oncogene-Driven Myeloid LeukemiaCécile K Lopez, Esteve Noguera, Vaia Stavropoulou, et al.
Blood|May 1, 2020
Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease driversAlexandre Fagnan, Frederik Otzen Bagger, Maria-Riera Piqué-Borràs, et al.
Cell|August 7, 2012
Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKLQiang Wen, Benjamin Goldenson, Serena J Silver, et al.
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