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EMBO Molecular Medicine|June 9, 2025
Small molecule disruption of RARα/NCoR1 interaction inhibits chaperone-mediated autophagy in cancerMericka McCabe, Rajanya Bhattacharyya, Rebecca Sereda, et al.Proceedings of the National Academy of Sciences of the United States of America|September 28, 2011
Rumi functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferaseHideyuki Takeuchi, Rodrigo C Fernández-Valdivia, Devin S Caswell, et al.Molecular Cell|February 17, 2015
Inhibition of Pro-apoptotic BAX by a noncanonical interaction mechanismLauren A Barclay, Thomas E Wales, Thomas P Garner, et al.Marine Drugs|July 31, 2014
Marinopyrrole derivatives with sulfide spacers as selective disruptors of Mcl-1 binding to pro-apoptotic protein BimChunwei Cheng, Yan Liu, Maria E Balasis, et al.Cancer Cell|October 11, 2017
Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid LeukemiaDenis E Reyna, Thomas P Garner, Andrea Lopez, et al.Nature Communications|July 21, 2022
Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degenerationRaquel Gomez-Sintes, Qisheng Xin, Juan Ignacio Jimenez-Loygorri, et al.Journal of Experimental & Clinical Cancer Research : CR|December 17, 2013
On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium saltsSara Iachettini, Malcolm Fg Stevens, Mark Frigerio, et al.ACS Omega|January 26, 2026
Targeting PTPN22 at Nonorthosteric Binding SitesA Fragment ApproachPaola Di Lello, Marta M Wells, Ben Davis, et al.Nature Communications|July 7, 2022
Modulating mitofusins to control mitochondrial function and signalingEmmanouil Zacharioudakis, Bogos Agianian, Vasantha Kumar Mv, et al.Nature Cancer|August 11, 2020
A small-molecule allosteric inhibitor of BAX protects against doxorubicin-induced cardiomyopathyDulguun Amgalan, Thomas P Garner, Ryan Pekson, et al.Pageof 3