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Bioconjugate Chemistry
|
April 3, 2025
Mechanistic Characterization of the Potency of THIOMAB Antibody-Drug Conjugates Targeting <i>Staphylococcus aureus</i> and ETbR-Expressing Tumor Cells Using Quantitative LC-MS/MS Analysis of Intracellular Drug Accumulation
Hilda Hernandez-Barry, Josefa Dela Cruz-Chuh, Kimberly K Kajihara, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
March 13, 2019
A Novel Depurination Methodology to Assess DNA Alkylation of Chloro-Bis-Seco-Cyclopropylbenzoindoles Allowed for Comparison of Minor-Groove Reactivity
Shuai Wang, Buyun Chen, Peter Dragovich, et al.
Molecular Cancer Therapeutics
|
December 4, 2020
An Anti-CD22-<i>seco</i>-CBI-Dimer Antibody-Drug Conjugate (ADC) for the Treatment of Non-Hodgkin Lymphoma That Provides a Longer Duration of Response than Auristatin-Based ADCs in Preclinical Models
Shang-Fan Yu, Donna W Lee, Bing Zheng, et al.
Nature Communications
|
March 23, 2018
Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes
David S Hewings, Johanna Heideker, Taylur P Ma, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
July 1, 2018
An Anti-CLL-1 Antibody-Drug Conjugate for the Treatment of Acute Myeloid Leukemia
Bing Zheng, Shang-Fan Yu, Geoffrey Del Rosario, et al.
Mbio
|
June 1, 2021
Potent Killing of Pseudomonas aeruginosa by an Antibody-Antibiotic Conjugate
Kimberly K Kajihara, Homer Pantua, Hilda Hernandez-Barry, et al.
Nature Communications
|
January 11, 2024
The HER2-directed antibody-drug conjugate DHES0815A in advanced and/or metastatic breast cancer: preclinical characterization and phase 1 trial results
Gail D Lewis, Guangmin Li, Jun Guo, et al.
Nature
|
November 5, 2015
Novel antibody-antibiotic conjugate eliminates intracellular S. aureus
Sophie M Lehar, Thomas Pillow, Min Xu, et al.
Chemical Science
|
April 13, 2022
A homogeneous high-DAR antibody-drug conjugate platform combining THIOMAB antibodies and XTEN polypeptides
Neelie Zacharias, Vladimir N Podust, Kimberly K Kajihara, et al.
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of 1
Search research articles
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Showing results (1-10 of 9) with videos related to
Sort By:
Page
of 1
Bioconjugate Chemistry
|
April 3, 2025
Mechanistic Characterization of the Potency of THIOMAB Antibody-Drug Conjugates Targeting <i>Staphylococcus aureus</i> and ETbR-Expressing Tumor Cells Using Quantitative LC-MS/MS Analysis of Intracellular Drug Accumulation
Hilda Hernandez-Barry, Josefa Dela Cruz-Chuh, Kimberly K Kajihara, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
March 13, 2019
A Novel Depurination Methodology to Assess DNA Alkylation of Chloro-Bis-Seco-Cyclopropylbenzoindoles Allowed for Comparison of Minor-Groove Reactivity
Shuai Wang, Buyun Chen, Peter Dragovich, et al.
Molecular Cancer Therapeutics
|
December 4, 2020
An Anti-CD22-<i>seco</i>-CBI-Dimer Antibody-Drug Conjugate (ADC) for the Treatment of Non-Hodgkin Lymphoma That Provides a Longer Duration of Response than Auristatin-Based ADCs in Preclinical Models
Shang-Fan Yu, Donna W Lee, Bing Zheng, et al.
Nature Communications
|
March 23, 2018
Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes
David S Hewings, Johanna Heideker, Taylur P Ma, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
July 1, 2018
An Anti-CLL-1 Antibody-Drug Conjugate for the Treatment of Acute Myeloid Leukemia
Bing Zheng, Shang-Fan Yu, Geoffrey Del Rosario, et al.
Mbio
|
June 1, 2021
Potent Killing of Pseudomonas aeruginosa by an Antibody-Antibiotic Conjugate
Kimberly K Kajihara, Homer Pantua, Hilda Hernandez-Barry, et al.
Nature Communications
|
January 11, 2024
The HER2-directed antibody-drug conjugate DHES0815A in advanced and/or metastatic breast cancer: preclinical characterization and phase 1 trial results
Gail D Lewis, Guangmin Li, Jun Guo, et al.
Nature
|
November 5, 2015
Novel antibody-antibiotic conjugate eliminates intracellular S. aureus
Sophie M Lehar, Thomas Pillow, Min Xu, et al.
Chemical Science
|
April 13, 2022
A homogeneous high-DAR antibody-drug conjugate platform combining THIOMAB antibodies and XTEN polypeptides
Neelie Zacharias, Vladimir N Podust, Kimberly K Kajihara, et al.
Page
of 1