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Immunologic Research|November 12, 2013
The IL-2/IL-2R system: from basic science to therapeutic applications to enhance immune regulationAllison L Bayer, Alberto Pugliese, Thomas R Malek
Immunity|March 13, 2024
Interleukin-2 signaling in the regulation of T cell biology in autoimmunity and cancerAcacia N Shouse, Kathryn M LaPorte, Thomas R Malek
Journal of Immunology (Baltimore, Md. : 1950)|June 24, 2004
Distinct activation signals determine whether IL-21 induces B cell costimulation, growth arrest, or Bim-dependent apoptosisHaoli Jin, Roberto Carrio, Aixin Yu, et al.
Iscience|January 6, 2025
Interleukin-2 receptor signaling acts as a checkpoint that influences the distribution of regulatory T cell subsetsAcacia N Shouse, Alejandro V Villarino, Thomas R Malek
The American Journal of Pathology|August 4, 2020
Medical Treatment Can Unintentionally Alter the Regulatory T-Cell Compartment in Patients with Widespread Pathophysiologic ConditionsSabrina N Copsel, Thomas R Malek, Robert B Levy
Journal of Immunology (Baltimore, Md. : 1950)|July 17, 2026
The transcription factor SREBP2 supports the activation and homeostasis of CD4+ Foxp3+ regulatory T cellsAcacia N Shouse, Alejandro V Villarino, Thomas R Malek
BMC Cancer|July 29, 2003
Therapeutic limitations in tumor-specific CD8+ memory T cell engraftmentOliver F Bathe, Nava Dalyot-Herman, Thomas R Malek
Journal of Immunology (Baltimore, Md. : 1950)|May 16, 2019
CD25 and Protein Phosphatase 2A Cooperate to Enhance IL-2R Signaling in Human Regulatory T CellsYing Ding, Aixin Yu, George C Tsokos, et al.
The Journal of Experimental Medicine|March 9, 2005
Essential role for interleukin-2 for CD4(+)CD25(+) T regulatory cell development during the neonatal periodAllison L Bayer, Aixin Yu, Dennis Adeegbe, et al.
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