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Cell Reports|April 21, 2026
Durable control of autoimmunity requires sustained stimulation of regulatory T cellsJanika Põder, Aixin Yu, Ying Ding, et al.Blood|October 4, 2008
Host CD4+CD25+ T cells can expand and comprise a major component of the Treg compartment after experimental HCTAllison L Bayer, Monica Jones, Jackeline Chirinos, et al.Transplantation|June 18, 2003
Long-term islet allograft survival in nonobese diabetic mice treated with tacrolimus, rapamycin, and anti-interleukin-2 antibodyR Damaris Molano, Antonello Pileggi, Thierry Berney, et al.Nature Immunology|April 22, 2022
Dynamic transcriptional activity and chromatin remodeling of regulatory T cells after varied duration of interleukin-2 receptor signalingAlejandro Moro, Zhen Gao, Lily Wang, et al.Science Signaling|December 21, 2017
Altered homeostasis and development of regulatory T cell subsets represent an IL-2R-dependent risk for diabetes in NOD miceConnor J Dwyer, Allison L Bayer, Carmen Fotino, et al.The Journal of Clinical Investigation|October 5, 2010
Therapeutic Treg expansion in mice by TNFRSF25 prevents allergic lung inflammationTaylor H Schreiber, Dietlinde Wolf, Matthew S Tsai, et al.Diabetes|August 27, 2020
Persistent IL-2 Receptor Signaling by IL-2/CD25 Fusion Protein Controls Diabetes in NOD Mice by Multiple MechanismsNatasha C Ward, Jen Bon Lui, Rosmely Hernandez, et al.Cell Death and Differentiation|December 3, 2016
Transient mitochondrial DNA double strand breaks in mice cause accelerated aging phenotypes in a ROS-dependent but p53/p21-independent mannerMilena Pinto, Alicia M Pickrell, Xiao Wang, et al.JCI Insight|August 7, 2025
BLIMP-1 and CEACAM1 cooperatively regulate human Treg homeostasis and function to control xenogeneic GVHDYing Ding, Aixin Yu, Milos Vujanac, et al.Journal of Immunology (Baltimore, Md. : 1950)|October 5, 2018
IL-2/CD25: A Long-Acting Fusion Protein That Promotes Immune Tolerance by Selectively Targeting the IL-2 Receptor on Regulatory T CellsNatasha C Ward, Aixin Yu, Alejandro Moro, et al.Pageof 8