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Thomas S Dexheimer

Showing results (1-10 of 66) with videos related to

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Nature Protocols|October 18, 2008
DNA cleavage assay for the identification of topoisomerase I inhibitorsThomas S Dexheimer, Yves Pommier
Journal of the American Chemical Society|April 20, 2006
Deconvoluting the structural and drug-recognition complexity of the G-quadruplex-forming region upstream of the bcl-2 P1 promoterThomas S Dexheimer, Daekyu Sun, Laurence H Hurley
Journal of Medicinal Chemistry|November 25, 2010
Design, synthesis, and evaluation of dibenzo[c,h][1,6]naphthyridines as topoisomerase I inhibitors and potential anticancer agentsEvgeny Kiselev, Thomas S Dexheimer, Yves Pommier, et al.
Anti-Cancer Agents in Medicinal Chemistry|May 14, 2008
Tyrosyl-DNA phosphodiesterase as a target for anticancer therapyThomas S Dexheimer, Smitha Antony, Christophe Marchand, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 3, 2010
Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondriaBenu Brata Das, Thomas S Dexheimer, Kasthuraiah Maddali, et al.
Molecular Cancer Therapeutics|June 4, 2011
Molecular and cellular pharmacology of the novel noncamptothecin topoisomerase I inhibitor Genz-644282Dhriti Sooryakumar, Thomas S Dexheimer, Beverly A Teicher, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 22, 2014
Neuroprotection and repair of 3'-blocking DNA ends by glaikit (gkt) encoding Drosophila tyrosyl-DNA phosphodiesterase 1 (TDP1)DongYu Guo, Thomas S Dexheimer, Yves Pommier, et al.
Bioorganic & Medicinal Chemistry|September 29, 2009
Synthesis and biological evaluation of 14-(aminoalkyl-aminomethyl)aromathecins as topoisomerase I inhibitors: investigating the hypothesis of shared structure-activity relationshipsMaris A Cinelli, Brenda Cordero, Thomas S Dexheimer, et al.
Nucleic Acids Research|June 14, 2008
The modulation of topoisomerase I-mediated DNA cleavage and the induction of DNA-topoisomerase I crosslinks by crotonaldehyde-derived DNA adductsThomas S Dexheimer, Albena Kozekova, Carmelo J Rizzo, et al.
ACS Chemical Biology|July 19, 2017
Small Molecule Enhancement of 20S Proteasome Activity Targets Intrinsically Disordered ProteinsCorey L Jones, Evert Njomen, Benita Sjögren, et al.
Pageof 7

Showing results (1-10 of 66) with videos related to

Sort By:
Pageof 7
Nature Protocols|October 18, 2008
DNA cleavage assay for the identification of topoisomerase I inhibitorsThomas S Dexheimer, Yves Pommier
Journal of the American Chemical Society|April 20, 2006
Deconvoluting the structural and drug-recognition complexity of the G-quadruplex-forming region upstream of the bcl-2 P1 promoterThomas S Dexheimer, Daekyu Sun, Laurence H Hurley
Journal of Medicinal Chemistry|November 25, 2010
Design, synthesis, and evaluation of dibenzo[c,h][1,6]naphthyridines as topoisomerase I inhibitors and potential anticancer agentsEvgeny Kiselev, Thomas S Dexheimer, Yves Pommier, et al.
Anti-Cancer Agents in Medicinal Chemistry|May 14, 2008
Tyrosyl-DNA phosphodiesterase as a target for anticancer therapyThomas S Dexheimer, Smitha Antony, Christophe Marchand, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 3, 2010
Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondriaBenu Brata Das, Thomas S Dexheimer, Kasthuraiah Maddali, et al.
Molecular Cancer Therapeutics|June 4, 2011
Molecular and cellular pharmacology of the novel noncamptothecin topoisomerase I inhibitor Genz-644282Dhriti Sooryakumar, Thomas S Dexheimer, Beverly A Teicher, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 22, 2014
Neuroprotection and repair of 3'-blocking DNA ends by glaikit (gkt) encoding Drosophila tyrosyl-DNA phosphodiesterase 1 (TDP1)DongYu Guo, Thomas S Dexheimer, Yves Pommier, et al.
Bioorganic & Medicinal Chemistry|September 29, 2009
Synthesis and biological evaluation of 14-(aminoalkyl-aminomethyl)aromathecins as topoisomerase I inhibitors: investigating the hypothesis of shared structure-activity relationshipsMaris A Cinelli, Brenda Cordero, Thomas S Dexheimer, et al.
Nucleic Acids Research|June 14, 2008
The modulation of topoisomerase I-mediated DNA cleavage and the induction of DNA-topoisomerase I crosslinks by crotonaldehyde-derived DNA adductsThomas S Dexheimer, Albena Kozekova, Carmelo J Rizzo, et al.
ACS Chemical Biology|July 19, 2017
Small Molecule Enhancement of 20S Proteasome Activity Targets Intrinsically Disordered ProteinsCorey L Jones, Evert Njomen, Benita Sjögren, et al.
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