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DNA Repair
|
May 11, 2018
Probing the evolutionary conserved residues Y204, F259, S400 and W590 that shape the catalytic groove of human TDP1 for 3'- and 5'-phosphodiester-DNA bond cleavage
Evgeny Kiselev, Thomas S Dexheimer, Christophe Marchand, et al.
The Journal of Biological Chemistry
|
July 9, 2020
Two highly related odorant receptors specifically detect α-bile acid pheromones in sea lamprey (<i>Petromyzon marinus</i>)
Zhe Zhang, Qinghua Zhang, Thomas S Dexheimer, et al.
Journal of Medicinal Chemistry
|
February 17, 2010
Structure-based design, synthesis, and biological studies of new anticancer norindenoisoquinoline topoisomerase I inhibitors
Yunlong Song, Zhiyu Shao, Thomas S Dexheimer, et al.
Nucleic Acids Research
|
January 26, 2010
The DNA binding and 3'-end preferential activity of human tyrosyl-DNA phosphodiesterase
Thomas S Dexheimer, Andrew G Stephen, Matthew J Fivash, et al.
Journal of Medicinal Chemistry
|
August 19, 2007
Nitrated indenoisoquinolines as topoisomerase I inhibitors: a systematic study and optimization
Andrew Morrell, Michael Placzek, Seth Parmley, et al.
Bioorganic & Medicinal Chemistry
|
July 21, 2018
Virtual screening using ligand-based pharmacophores for inhibitors of human tyrosyl-DNA phospodiesterase (hTdp1)
Iwona E Weidlich, Thomas S Dexheimer, Christophe Marchand, et al.
Journal of Medicinal Chemistry
|
July 18, 2008
Design, synthesis, and biological evaluation of 14-substituted aromathecins as topoisomerase I inhibitors
Maris A Cinelli, Andrew Morrell, Thomas S Dexheimer, et al.
Journal of Medicinal Chemistry
|
August 10, 2011
7-azaindenoisoquinolines as topoisomerase I inhibitors and potential anticancer agents
Evgeny Kiselev, Sean DeGuire, Andrew Morrell, et al.
Journal of the American Chemical Society
|
January 26, 2006
An intramolecular G-quadruplex structure with mixed parallel/antiparallel G-strands formed in the human BCL-2 promoter region in solution
Jixun Dai, Thomas S Dexheimer, Ding Chen, et al.
The Journal of Biological Chemistry
|
March 1, 2012
Tyrosyl-DNA phosphodiesterase 1 (TDP1) repairs DNA damage induced by topoisomerases I and II and base alkylation in vertebrate cells
Junko Murai, Shar-yin N Huang, Benu Brata Das, et al.
Page
of 7
Search research articles
Search
Showing results (11-20 of 66) with videos related to
Sort By:
Page
of 7
DNA Repair
|
May 11, 2018
Probing the evolutionary conserved residues Y204, F259, S400 and W590 that shape the catalytic groove of human TDP1 for 3'- and 5'-phosphodiester-DNA bond cleavage
Evgeny Kiselev, Thomas S Dexheimer, Christophe Marchand, et al.
The Journal of Biological Chemistry
|
July 9, 2020
Two highly related odorant receptors specifically detect α-bile acid pheromones in sea lamprey (<i>Petromyzon marinus</i>)
Zhe Zhang, Qinghua Zhang, Thomas S Dexheimer, et al.
Journal of Medicinal Chemistry
|
February 17, 2010
Structure-based design, synthesis, and biological studies of new anticancer norindenoisoquinoline topoisomerase I inhibitors
Yunlong Song, Zhiyu Shao, Thomas S Dexheimer, et al.
Nucleic Acids Research
|
January 26, 2010
The DNA binding and 3'-end preferential activity of human tyrosyl-DNA phosphodiesterase
Thomas S Dexheimer, Andrew G Stephen, Matthew J Fivash, et al.
Journal of Medicinal Chemistry
|
August 19, 2007
Nitrated indenoisoquinolines as topoisomerase I inhibitors: a systematic study and optimization
Andrew Morrell, Michael Placzek, Seth Parmley, et al.
Bioorganic & Medicinal Chemistry
|
July 21, 2018
Virtual screening using ligand-based pharmacophores for inhibitors of human tyrosyl-DNA phospodiesterase (hTdp1)
Iwona E Weidlich, Thomas S Dexheimer, Christophe Marchand, et al.
Journal of Medicinal Chemistry
|
July 18, 2008
Design, synthesis, and biological evaluation of 14-substituted aromathecins as topoisomerase I inhibitors
Maris A Cinelli, Andrew Morrell, Thomas S Dexheimer, et al.
Journal of Medicinal Chemistry
|
August 10, 2011
7-azaindenoisoquinolines as topoisomerase I inhibitors and potential anticancer agents
Evgeny Kiselev, Sean DeGuire, Andrew Morrell, et al.
Journal of the American Chemical Society
|
January 26, 2006
An intramolecular G-quadruplex structure with mixed parallel/antiparallel G-strands formed in the human BCL-2 promoter region in solution
Jixun Dai, Thomas S Dexheimer, Ding Chen, et al.
The Journal of Biological Chemistry
|
March 1, 2012
Tyrosyl-DNA phosphodiesterase 1 (TDP1) repairs DNA damage induced by topoisomerases I and II and base alkylation in vertebrate cells
Junko Murai, Shar-yin N Huang, Benu Brata Das, et al.
Page
of 7