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Science Translational Medicine
|
June 5, 2024
Peripheral expression of brain-penetrant progranulin rescues pathologies in mouse models of frontotemporal lobar degeneration
Marvin Reich, Matthew J Simon, Beate Polke, et al.
Neuron
|
January 7, 2020
TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge
Alicia A Nugent, Karin Lin, Bettina van Lengerich, et al.
Nature Communications
|
February 20, 2025
Fc-engineered large molecules targeting blood-brain barrier transferrin receptor and CD98hc have distinct central nervous system and peripheral biodistribution
Nathalie Khoury, Michelle E Pizzo, Claire B Discenza, et al.
The Journal of Prevention of Alzheimer'S Disease
|
December 1, 2025
Towards an AI biomedical scientist: Accelerating discoveries in neurodegenerative disease
Kaleigh F Roberts, Eric C Landsness, Justin Reese, et al.
Nature Communications
|
April 15, 2026
Author Correction: Fc-engineered large molecules targeting blood-brain barrier transferrin receptor and CD98hc have distinct central nervous system and peripheral biodistribution
Nathalie Khoury, Michelle E Pizzo, Claire B Discenza, et al.
Movement Disorders : Official Journal of the Movement Disorder Society
|
November 28, 2023
The Genetic Drivers of Juvenile, Young, and Early-Onset Parkinson's Disease in India
Shan V Andrews, Prashanth L Kukkle, Ramesh Menon, et al.
Elife
|
September 17, 2024
DNL343 is an investigational CNS penetrant eukaryotic initiation factor 2B activator that prevents and reverses the effects of neurodegeneration caused by the integrated stress response
Ernie Yulyaningsih, Jung H Suh, Melania Fanok, et al.
Cell
|
November 12, 2024
Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes
Jing L Guo, Dylan Braun, Gabriel A Fitzgerald, et al.
Science Translational Medicine
|
May 29, 2020
Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice
Julie C Ullman, Annie Arguello, Jennifer A Getz, et al.
Nature Communications
|
August 18, 2025
Investigational eIF2B activator DNL343 modulates the integrated stress response in preclinical models of TDP-43 pathology and individuals with ALS in a randomized clinical trial
Brittany N Flores, Seungyoon B Yu, Isaac V Cohen, et al.
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of 5
Search research articles
Search
Showing results (31-40 of 42) with videos related to
Sort By:
Page
of 5
Science Translational Medicine
|
June 5, 2024
Peripheral expression of brain-penetrant progranulin rescues pathologies in mouse models of frontotemporal lobar degeneration
Marvin Reich, Matthew J Simon, Beate Polke, et al.
Neuron
|
January 7, 2020
TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge
Alicia A Nugent, Karin Lin, Bettina van Lengerich, et al.
Nature Communications
|
February 20, 2025
Fc-engineered large molecules targeting blood-brain barrier transferrin receptor and CD98hc have distinct central nervous system and peripheral biodistribution
Nathalie Khoury, Michelle E Pizzo, Claire B Discenza, et al.
The Journal of Prevention of Alzheimer'S Disease
|
December 1, 2025
Towards an AI biomedical scientist: Accelerating discoveries in neurodegenerative disease
Kaleigh F Roberts, Eric C Landsness, Justin Reese, et al.
Nature Communications
|
April 15, 2026
Author Correction: Fc-engineered large molecules targeting blood-brain barrier transferrin receptor and CD98hc have distinct central nervous system and peripheral biodistribution
Nathalie Khoury, Michelle E Pizzo, Claire B Discenza, et al.
Movement Disorders : Official Journal of the Movement Disorder Society
|
November 28, 2023
The Genetic Drivers of Juvenile, Young, and Early-Onset Parkinson's Disease in India
Shan V Andrews, Prashanth L Kukkle, Ramesh Menon, et al.
Elife
|
September 17, 2024
DNL343 is an investigational CNS penetrant eukaryotic initiation factor 2B activator that prevents and reverses the effects of neurodegeneration caused by the integrated stress response
Ernie Yulyaningsih, Jung H Suh, Melania Fanok, et al.
Cell
|
November 12, 2024
Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes
Jing L Guo, Dylan Braun, Gabriel A Fitzgerald, et al.
Science Translational Medicine
|
May 29, 2020
Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice
Julie C Ullman, Annie Arguello, Jennifer A Getz, et al.
Nature Communications
|
August 18, 2025
Investigational eIF2B activator DNL343 modulates the integrated stress response in preclinical models of TDP-43 pathology and individuals with ALS in a randomized clinical trial
Brittany N Flores, Seungyoon B Yu, Isaac V Cohen, et al.
Page
of 5