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Journal of Virology|February 9, 2007
Characterization of a replication-competent, integrase-defective human immunodeficiency virus (HIV)/simian virus 40 chimera as a powerful tool for the discovery and validation of HIV integrase inhibitorsDirk Daelemans, Richard Lu, Erik De Clercq, et al.
Nature Protocols|June 4, 2011
A time-of-drug addition approach to target identification of antiviral compoundsDirk Daelemans, Rudi Pauwels, Erik De Clercq, et al.
Proteins|March 27, 2012
Computational investigation of the HIV-1 Rev multimerization using molecular dynamics simulations and binding free energy calculationsTom Venken, Dirk Daelemans, Marc De Maeyer, et al.
Nature Communications|February 7, 2018
Target identification of small molecules using large-scale CRISPR-Cas mutagenesis scanning of essential genesJasper Edgar Neggers, Bert Kwanten, Tim Dierckx, et al.
ACS Medicinal Chemistry Letters|August 25, 2020
Synthesis and Antitumor Activity of C-7-Alkynylated and Arylated Pyrrolotriazine C-RibonucleosidesQingfeng Li, Elisabetta Groaz, Leentje Persoons, et al.
Bioorganic & Medicinal Chemistry Letters|April 2, 2016
L-Aspartic and l-glutamic acid ester-based ProTides of anticancer nucleosides: Synthesis and antitumoral evaluationLing-Jie Gao, Steven De Jonghe, Dirk Daelemans, et al.
Molecular and Cellular Biology|January 6, 2005
Kinetic and molecular analysis of nuclear export factor CRM1 association with its cargo in vivoDirk Daelemans, Sylvain V Costes, Stephen Lockett, et al.
Ebiomedicine|October 27, 2015
Human Exportin-1 is a Target for Combined Therapy of HIV and AIDS Related LymphomaEline Boons, Els Vanstreels, Maarten Jacquemyn, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|November 1, 2016
The Second-Generation Exportin-1 Inhibitor KPT-8602 Demonstrates Potent Activity against Acute Lymphoblastic LeukemiaThomas Vercruysse, Jolien De Bie, Jasper E Neggers, et al.
RSC Advances|July 13, 2026
Unveiling acetamide coupled benzothiazole hydrazones as potential anti-proliferative agents: an experimental and computational approachMahnoor Imtiaz, Leentje Persoons, Dirk Daelemans, et al.
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