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Pharmacogenetics and Genomics|June 23, 2010
Integration of high-throughput genotyping data into pharmacometric analyses using nonlinear mixed effects modelingThorsten Lehr, Hans-Guenter Schaefer, Alexander StaabClinical Pharmacokinetics|December 17, 2009
Semi-mechanistic population pharmacokinetic drug-drug interaction modelling of a long half-life substrate and itraconazoleThorsten Lehr, Alexander Staab, Dirk Trommeshauser, et al.The AAPS Journal|January 16, 2010
Quantitative pharmacology approach in Alzheimer's disease: efficacy modeling of early clinical data to predict clinical outcome of tesofensineThorsten Lehr, Alexander Staab, Dirk Trommeshauser, et al.Clinical Pharmacokinetics|August 27, 2009
A quantitative enterohepatic circulation model: development and evaluation with tesofensine and meloxicamThorsten Lehr, Alexander Staab, Christiane Tillmann, et al.British Journal of Clinical Pharmacology|February 28, 2007
Population pharmacokinetic modelling of NS2330 (tesofensine) and its major metabolite in patients with Alzheimer's diseaseThorsten Lehr, Alexander Staab, Christiane Tillmann, et al.Pharmacogenetics and Genomics|August 24, 2011
Integration of absorption, distribution, metabolism, and elimination genotyping data into a population pharmacokinetic analysis of nevirapineThorsten Lehr, Jing Yuan, David Hall, et al.Journal of Clinical Pharmacology|May 29, 2013
A semi-physiological model of amyloid-β biosynthesis and clearance in human cerebrospinal fluid: a tool for alzheimer's disease research and drug developmentKarin G Haug, Alexander Staab, Chantaratsamon Dansirikul, et al.Clinical Pharmacokinetics|March 27, 2013
Pharmacometric characterization of dabigatran hemodialysisKarl-Heinz Liesenfeld, Alexander Staab, Sebastian Härtter, et al.Journal of Clinical Pharmacology|September 30, 2011
Dabigatran etexilate in atrial fibrillation patients with severe renal impairment: dose identification using pharmacokinetic modeling and simulationThorsten Lehr, Sebastian Haertter, Karl-Heinz Liesenfeld, et al.European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|April 6, 2007
Effective integration of systems biology, biomarkers, biosimulation and modelling in streamlining drug developmentRajesh Krishna, Hans Guenter Schaefer, Ole J BjerrumPageof 16