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Organic Letters|September 27, 2002
Sequencing hydroxyethylamine-containing peptides via Edman degradationMatthias Brewer, Thorsten Oost, Chanokporn Sukonpan, et al.Biopolymers|March 3, 2004
Design and synthesis of substrate-based inhibitors of botulinum neurotoxin type B metalloproteaseThorsten Oost, Chanokporn Sukonpan, Matthias Brewer, et al.Bioorganic & Medicinal Chemistry Letters|August 13, 2018
Novel, potent, selective and brain penetrant vasopressin 1b receptor antagonistsHervé Geneste, Swati Bhowmik, Marcel M van Gaalen, et al.Bioorganic & Medicinal Chemistry Letters|May 25, 2011
Potent and selective oxindole-based vasopressin 1b receptor antagonists with improved pharmacokinetic propertiesThorsten Oost, Gisela Backfisch, Swati Bhowmik, et al.Bioorganic & Medicinal Chemistry Letters|June 17, 2015
Design, synthesis and evaluation of MCH receptor 1 antagonists--Part II: Optimization of pyridazines toward reduced phospholipidosis and hERG inhibitionGerald J Roth, Armin Heckel, Jörg T Kley, et al.Bioorganic & Medicinal Chemistry Letters|June 25, 2015
Design, synthesis and evaluation of MCH receptor 1 antagonists--Part III: Discovery of pre-clinical development candidate BI 186908Thorsten Oost, Armin Heckel, Jörg T Kley, et al.Bioorganic & Medicinal Chemistry Letters|June 27, 2015
Design, synthesis and evaluation of MCH receptor 1 antagonists--Part I: Optimization of HTS hits towards an in vivo efficacious tool compound BI 414Stephan G Müller, Armin Heckel, Jörg T Kley, et al.Journal of Medicinal Chemistry|July 14, 2023
Discovery of BI 7446: A Potent Cyclic Dinucleotide STING Agonist with Broad-Spectrum Variant Activity for the Treatment of CancerChristian A Kuttruff, Martin Fleck, Sebastian Carotta, et al.Bioorganic & Medicinal Chemistry Letters|September 28, 2010
Discovery of a potent and selective Bcl-2 inhibitor using SAR by NMRAndrew M Petros, Jeffrey R Huth, Thorsten Oost, et al.Pageof 1