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The EMBO Journal|August 26, 2015
RuvbL1 and RuvbL2 enhance aggresome formation and disaggregate amyloid fibrilsNava Zaarur, Xiaobin Xu, Patrick Lestienne, et al.
RSC Chemical Biology|August 30, 2021
Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitorsJoão D Seixas, Bárbara B Sousa, Marta C Marques, et al.
Journal of Molecular Biology|July 28, 2022
Deciphering cellular and molecular determinants of human DPCD protein in complex with RUVBL1/RUVBL2 AAA-ATPasesRaphael Dos Santos Morais, Paulo E Santo, Marie Ley, et al.
Nature Communications|May 31, 2018
The RPAP3-Cterminal domain identifies R2TP-like quaternary chaperonesChloé Maurizy, Marc Quinternet, Yoann Abel, et al.
Journal of Medicinal Chemistry|June 28, 2022
Optimization of TEAD P-Site Binding Fragment Hit into In Vivo Active Lead MSC-4106Timo Heinrich, Carl Peterson, Richard Schneider, et al.
Journal of Medicinal Chemistry|December 20, 2024
MoA Studies of the TEAD P-Site Binding Ligand MSC-4106 and Its Optimization to TEAD1-Selective Amide M3686Timo Heinrich, Daniel Schwarz, Carl Petersson, et al.
Cell Chemical Biology|November 29, 2024
An engineered cereblon optimized for high-throughput screening and molecular glue discoveryHenry J Bailey, Jonathan Eisert, Rubina Kazi, et al.
Journal of Medicinal Chemistry|November 10, 2025
Phenotypic Hit Identification and Optimization of Novel Pan-TEAD and Subtype-Selective InhibitorsTimo Heinrich, Alessia Gambardella, Daniel Schwarz, et al.
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