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Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
September 21, 2014
Ponatinib inhibits polyclonal drug-resistant KIT oncoproteins and shows therapeutic potential in heavily pretreated gastrointestinal stromal tumor (GIST) patients
Andrew P Garner, Joseph M Gozgit, Rana Anjum, et al.
Journal of Medicinal Chemistry
|
January 11, 2013
Fragment growing and linking lead to novel nanomolar lactate dehydrogenase inhibitors
Anna Kohlmann, Stephan G Zech, Feng Li, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
November 1, 2016
The Potent ALK Inhibitor Brigatinib (AP26113) Overcomes Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in Preclinical Models
Sen Zhang, Rana Anjum, Rachel Squillace, et al.
British Journal of Cancer
|
November 21, 2021
Once weekly selinexor, carfilzomib and dexamethasone in carfilzomib non-refractory multiple myeloma patients
Cristina Gasparetto, Gary J Schiller, Sascha A Tuchman, et al.
Cancer Cell
|
November 3, 2009
AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance
Thomas O'Hare, William C Shakespeare, Xiaotian Zhu, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 13, 2011
Discovery of 5-(arenethynyl) hetero-monocyclic derivatives as potent inhibitors of BCR-ABL including the T315I gatekeeper mutant
Mathew Thomas, Wei-Sheng Huang, David Wen, et al.
Journal of Medicinal Chemistry
|
May 5, 2016
Discovery of Brigatinib (AP26113), a Phosphine Oxide-Containing, Potent, Orally Active Inhibitor of Anaplastic Lymphoma Kinase
Wei-Sheng Huang, Shuangying Liu, Dong Zou, et al.
Journal of Medicinal Chemistry
|
June 2, 2010
Discovery of 3-[2-(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide (AP24534), a potent, orally active pan-inhibitor of breakpoint cluster region-abelson (BCR-ABL) kinase including the T315I gatekeeper mutant
Wei-Sheng Huang, Chester A Metcalf, Raji Sundaramoorthi, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 24, 2022
Discovery of mobocertinib, a potent, oral inhibitor of EGFR exon 20 insertion mutations in non-small cell lung cancer
Wei-Sheng Huang, Feng Li, Yongjin Gong, et al.
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Search research articles
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Showing results (81-90 of 89) with videos related to
Sort By:
Page
of 9
You have reached the last page of results.
This site can display upto 89 results.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
September 21, 2014
Ponatinib inhibits polyclonal drug-resistant KIT oncoproteins and shows therapeutic potential in heavily pretreated gastrointestinal stromal tumor (GIST) patients
Andrew P Garner, Joseph M Gozgit, Rana Anjum, et al.
Journal of Medicinal Chemistry
|
January 11, 2013
Fragment growing and linking lead to novel nanomolar lactate dehydrogenase inhibitors
Anna Kohlmann, Stephan G Zech, Feng Li, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
November 1, 2016
The Potent ALK Inhibitor Brigatinib (AP26113) Overcomes Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in Preclinical Models
Sen Zhang, Rana Anjum, Rachel Squillace, et al.
British Journal of Cancer
|
November 21, 2021
Once weekly selinexor, carfilzomib and dexamethasone in carfilzomib non-refractory multiple myeloma patients
Cristina Gasparetto, Gary J Schiller, Sascha A Tuchman, et al.
Cancer Cell
|
November 3, 2009
AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance
Thomas O'Hare, William C Shakespeare, Xiaotian Zhu, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 13, 2011
Discovery of 5-(arenethynyl) hetero-monocyclic derivatives as potent inhibitors of BCR-ABL including the T315I gatekeeper mutant
Mathew Thomas, Wei-Sheng Huang, David Wen, et al.
Journal of Medicinal Chemistry
|
May 5, 2016
Discovery of Brigatinib (AP26113), a Phosphine Oxide-Containing, Potent, Orally Active Inhibitor of Anaplastic Lymphoma Kinase
Wei-Sheng Huang, Shuangying Liu, Dong Zou, et al.
Journal of Medicinal Chemistry
|
June 2, 2010
Discovery of 3-[2-(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide (AP24534), a potent, orally active pan-inhibitor of breakpoint cluster region-abelson (BCR-ABL) kinase including the T315I gatekeeper mutant
Wei-Sheng Huang, Chester A Metcalf, Raji Sundaramoorthi, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 24, 2022
Discovery of mobocertinib, a potent, oral inhibitor of EGFR exon 20 insertion mutations in non-small cell lung cancer
Wei-Sheng Huang, Feng Li, Yongjin Gong, et al.
Page
of 9