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Neurobiology of Disease|December 17, 2017
Familial knockin mutation of LRRK2 causes lysosomal dysfunction and accumulation of endogenous insoluble α-synuclein in neuronsJason Schapansky, Saurabh Khasnavis, Mark P DeAndrade, et al.
The EMBO Journal|September 16, 2010
Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1Frits Kamp, Nicole Exner, Anne Kathrin Lutz, et al.
Biorxiv : the Preprint Server for Biology|December 3, 2025
Lipid droplets promote the aberrant liquid-liquid phase separation of alpha-synuclein leading to impaired energy homeostasisJose Cevallos, Elena Eubanks, Sunghoo Jung, et al.
Human Molecular Genetics|September 16, 2017
Loss of native α-synuclein multimerization by strategically mutating its amphipathic helix causes abnormal vesicle interactions in neuronal cellsUlf Dettmer, Nagendran Ramalingam, Victoria E von Saucken, et al.
Acta Neuropathologica|February 10, 2022
Brain region-specific susceptibility of Lewy body pathology in synucleinopathies is governed by α-synuclein conformationsLaura de Boni, Aurelia Hays Watson, Ludovica Zaccagnini, et al.
Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids|June 17, 2023
GM1 oligosaccharide efficacy against α-synuclein aggregation and toxicity in vitroMaria Fazzari, Erika Di Biase, Ludovica Zaccagnini, et al.
Brain Communications|April 14, 2020
Analysis of α-synuclein species enriched from cerebral cortex of humans with sporadic dementia with Lewy bodiesJohn B Sanderson, Suman De, Haiyang Jiang, et al.
Brain : a Journal of Neurology|September 6, 2023
MerTK is a mediator of alpha-synuclein fibril uptake by human microgliaMarie-France Dorion, Moein Yaqubi, Konstantin Senkevich, et al.
EMBO Reports|July 2, 2026
Lipid droplets promote aberrant liquid-liquid phase separation of alpha-synuclein impairing energy homeostasisJose Cevallos, Elena Eubanks, Sunghoo Jung, et al.
Science (New York, N.Y.)|September 2, 2017
β2-Adrenoreceptor is a regulator of the α-synuclein gene driving risk of Parkinson's diseaseShuchi Mittal, Kjetil Bjørnevik, Doo Soon Im, et al.
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