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Cell Stem Cell|February 10, 2009
Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cellsTim C P Somervaille, Christina J Matheny, Gary J Spencer, et al.British Journal of Haematology|April 16, 2003
Intraocular relapse of childhood acute lymphoblastic leukaemiaTim C P Somervaille, Ian M Hann, Georgina Harrison, et al.Journal of Medicinal Chemistry|September 12, 2017
Development of (4-Cyanophenyl)glycine Derivatives as Reversible Inhibitors of Lysine Specific Demethylase 1Daniel P Mould, Cristina Alli, Ulf Bremberg, et al.Proceedings of the National Academy of Sciences of the United States of America|September 25, 2023
A TIAM1-TRIM28 complex mediates epigenetic silencing of protocadherins to promote migration of lung cancer cellsLucy Ginn, Joe Maltas, Martin J Baker, et al.Plos One|June 19, 2013
Phosphorylation of the leukemic oncoprotein EVI1 on serine 196 modulates DNA binding, transcriptional repression and transforming abilityDaniel J White, Richard D Unwin, Eric Bindels, et al.Cell Reports|September 22, 2021
Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemiaFabrizio Simeoni, Isabel Romero-Camarero, Francesco Camera, et al.Cancer Cell|April 3, 2012
The histone demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cellsWilliam J Harris, Xu Huang, James T Lynch, et al.Blood Neoplasia|June 2, 2025
Addition of navitoclax to ruxolitinib for patients with myelofibrosis with progression or suboptimal responseNaveen Pemmaraju, Tim C P Somervaille, Francesca Palandri, et al.Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology|October 14, 2020
First-in-Human Phase I Study of Iadademstat (ORY-1001): A First-in-Class Lysine-Specific Histone Demethylase 1A Inhibitor, in Relapsed or Refractory Acute Myeloid LeukemiaOlga Salamero, Pau Montesinos, Christophe Willekens, et al.Oncogene|September 28, 2022
HMG20B stabilizes association of LSD1 with GFI1 on chromatin to confer transcription repression and leukemia cell differentiation blockAlba Maiques-Diaz, Luciano Nicosia, Naseer J Basma, et al.Pageof 8