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Nature Neuroscience|October 28, 2016
Translating genome-wide association findings into new therapeutics for psychiatryGerome Breen, Qingqin Li, Bryan L Roth, et al.Nature|December 9, 2021
Structures of the σ2 receptor enable docking for bioactive ligand discoveryAssaf Alon, Jiankun Lyu, Joao M Braz, et al.ACS Medicinal Chemistry Letters|January 24, 2014
Discovery of β2 Adrenergic Receptor Ligands Using Biosensor Fragment Screening of Tagged Wild-Type ReceptorTonia Aristotelous, Seungkirl Ahn, Arun K Shukla, et al.Chemical Science|May 8, 2018
High-throughput identification of G protein-coupled receptor modulators through affinity mass spectrometry screeningShanshan Qin, Mengmeng Meng, Dehua Yang, et al.Nature Chemical Biology|May 31, 2016
Zebrafish behavioral profiling identifies multitarget antipsychotic-like compoundsGiancarlo Bruni, Andrew J Rennekamp, Andrea Velenich, et al.The Journal of Pain|December 31, 2013
Mechanistic insights into the analgesic efficacy of A-1264087, a novel neuronal Ca(2+) channel blocker that reduces nociception in rat preclinical pain modelsChang Z Zhu, Timothy A Vortherms, Min Zhang, et al.Nature|August 18, 2016
Structure-based discovery of opioid analgesics with reduced side effectsAashish Manglik, Henry Lin, Dipendra K Aryal, et al.Nature|November 3, 2009
Predicting new molecular targets for known drugsMichael J Keiser, Vincent Setola, John J Irwin, et al.Proceedings of the National Academy of Sciences of the United States of America|October 26, 2011
Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacyJohn A Allen, Julianne M Yost, Vincent Setola, et al.British Journal of Pharmacology|February 2, 2022
Community guidelines for GPCR ligand bias: IUPHAR review 32Peter Kolb, Terry Kenakin, Stephen P H Alexander, et al.Pageof 44