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Frontiers in Molecular Biosciences|November 16, 2020
Network Simulations Reveal Molecular Signatures of Vulnerability to Age-Dependent Stress and Tau AccumulationTimothy E Hoffman, William H Hanneman, Julie A MorenoAging Cell|August 18, 2017
A multimethod computational simulation approach for investigating mitochondrial dynamics and dysfunction in degenerative agingTimothy E Hoffman, Katherine J Barnett, Lyle Wallis, et al.Nature Communications|March 20, 2021
Melanoma subpopulations that rapidly escape MAPK pathway inhibition incur DNA damage and rely on stress signallingChen Yang, Chengzhe Tian, Timothy E Hoffman, et al.Biorxiv : the Preprint Server for Biology|March 30, 2023
Multiple cancer types rapidly escape from multiple MAPK inhibitors to generate mutagenesis-prone subpopulationsTimothy E Hoffman, Chen Yang, Varuna Nangia, et al.Cell Systems|January 16, 2025
CDK2 activity crosstalk on the ERK kinase translocation reporter can be resolved computationallyTimothy E Hoffman, Chengzhe Tian, Varuna Nangia, et al.Archives of Toxicology|December 21, 2018
Ultrasensitivity dynamics of diverse aryl hydrocarbon receptor modulators in a hepatoma cell lineTimothy E Hoffman, Evan R Acerbo, Kasimir F Carranza, et al.Science Signaling|August 1, 2023
Multiple cancers escape from multiple MAPK pathway inhibitors and use DNA replication stress signaling to tolerate aberrant cell cyclesTimothy E Hoffman, Varuna Nangia, C Ryland Ill, et al.Advanced Materials (Deerfield Beach, Fla.)|June 7, 2022
Intracellular Crowding by Bio-Orthogonal Hydrogel Formation Induces Reversible Molecular StasisLaura J Macdougall, Timothy E Hoffman, Bruce E Kirkpatrick, et al.Biomacromolecules|February 25, 2025
Design and Synthesis of Hydrolytically Degradable PEG Carbamate, Carbonate, and Ester Derivatives to Induce Reversible BiostasisGopal Reddy Sama, Meagan N Arguien, Timothy E Hoffman, et al.Advanced Healthcare Materials|December 24, 2023
Reversible Intracellular Gelation of MCF10A Cells Enables Programmable Control Over 3D Spheroid GrowthDelaney L McNally, Laura J Macdougall, Bruce E Kirkpatrick, et al.Pageof 2