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Timothy K Maclachlan

Showing results (11-20 of 23) with videos related to

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The Journal of Biological Chemistry|April 18, 2003
BRCA1 augments transcription by the NF-kappaB transcription factor by binding to the Rel domain of the p65/RelA subunitMiriam Benezra, Nathalie Chevallier, Debra J Morrison, et al.
Cancer Biology & Therapy|November 15, 2006
Insulin-like growth factor factor binding protein-2 is a novel mediator of p53 inhibition of insulin-like growth factor signalingAdda Grimberg, Carrie M Coleman, Zonggao Shi, et al.
Human Gene Therapy|August 22, 2022
Regulatory Consideration for the Nonclinical Safety Assessment of Gene TherapiesJeffrey S Moffit, Diann L Blanset, Jessica L Lynch, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|October 26, 2011
Nonclinical evaluation of GMA161--an antihuman CD16 (FcγRIII) monoclonal antibody for treatment of autoimmune disorders in CD16 transgenic miceMeghan M Flaherty, Timothy K MacLachlan, Misty Troutt, et al.
Mabs|May 6, 2017
Challenges and opportunities for the future of monoclonal antibody development: Improving safety assessment and reducing animal useFiona Sewell, Kathryn Chapman, Jessica Couch, et al.
Molecular Therapy. Methods & Clinical Development|January 24, 2018
Nonclinical Safety Evaluation of scAAV8-<i>RLBP1</i> for Treatment of <i>RLBP1</i> Retinitis PigmentosaTimothy K MacLachlan, Mark N Milton, Oliver Turner, et al.
Regulatory Toxicology and Pharmacology : RTP|November 21, 2020
Industry experiences with immune-mediated findings in biotherapeutic nonclinical toxicology studiesTimothy K MacLachlan, Sven Kronenberg, Nikki Marshall, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|December 2, 2010
Preclinical safety evaluation of AAV2-sFLT01- a gene therapy for age-related macular degenerationTimothy K Maclachlan, Michael Lukason, Margaret Collins, et al.
Regulatory Toxicology and Pharmacology : RTP|March 22, 2017
Inflammation and immunogenicity limit the utility of the rabbit as a nonclinical species for ocular biologic therapeuticsChristina L Zuch de Zafra, Vito G Sasseville, Steven Matsumoto, et al.
Regulatory Toxicology and Pharmacology : RTP|April 23, 2017
Corrigendum to "Inflammation and immunogenicity limit the utility of the rabbit as a nonclinical species for ocular biologic therapeutics" [Regul. Toxicol. Pharmacol. (2017) 221-230]Christina L Zuch de Zafra, Vito G Sasseville, Steven Matsumoto, et al.
Pageof 3

Showing results (11-20 of 23) with videos related to

Sort By:
Pageof 3
The Journal of Biological Chemistry|April 18, 2003
BRCA1 augments transcription by the NF-kappaB transcription factor by binding to the Rel domain of the p65/RelA subunitMiriam Benezra, Nathalie Chevallier, Debra J Morrison, et al.
Cancer Biology & Therapy|November 15, 2006
Insulin-like growth factor factor binding protein-2 is a novel mediator of p53 inhibition of insulin-like growth factor signalingAdda Grimberg, Carrie M Coleman, Zonggao Shi, et al.
Human Gene Therapy|August 22, 2022
Regulatory Consideration for the Nonclinical Safety Assessment of Gene TherapiesJeffrey S Moffit, Diann L Blanset, Jessica L Lynch, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|October 26, 2011
Nonclinical evaluation of GMA161--an antihuman CD16 (FcγRIII) monoclonal antibody for treatment of autoimmune disorders in CD16 transgenic miceMeghan M Flaherty, Timothy K MacLachlan, Misty Troutt, et al.
Mabs|May 6, 2017
Challenges and opportunities for the future of monoclonal antibody development: Improving safety assessment and reducing animal useFiona Sewell, Kathryn Chapman, Jessica Couch, et al.
Molecular Therapy. Methods & Clinical Development|January 24, 2018
Nonclinical Safety Evaluation of scAAV8-<i>RLBP1</i> for Treatment of <i>RLBP1</i> Retinitis PigmentosaTimothy K MacLachlan, Mark N Milton, Oliver Turner, et al.
Regulatory Toxicology and Pharmacology : RTP|November 21, 2020
Industry experiences with immune-mediated findings in biotherapeutic nonclinical toxicology studiesTimothy K MacLachlan, Sven Kronenberg, Nikki Marshall, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|December 2, 2010
Preclinical safety evaluation of AAV2-sFLT01- a gene therapy for age-related macular degenerationTimothy K Maclachlan, Michael Lukason, Margaret Collins, et al.
Regulatory Toxicology and Pharmacology : RTP|March 22, 2017
Inflammation and immunogenicity limit the utility of the rabbit as a nonclinical species for ocular biologic therapeuticsChristina L Zuch de Zafra, Vito G Sasseville, Steven Matsumoto, et al.
Regulatory Toxicology and Pharmacology : RTP|April 23, 2017
Corrigendum to "Inflammation and immunogenicity limit the utility of the rabbit as a nonclinical species for ocular biologic therapeutics" [Regul. Toxicol. Pharmacol. (2017) 221-230]Christina L Zuch de Zafra, Vito G Sasseville, Steven Matsumoto, et al.
Pageof 3