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Journal of Pharmacokinetics and Pharmacodynamics|March 3, 2024
Employing zero-inflated beta distribution in an exposure-response analysis of TYK2/JAK1 inhibitor brepocitinib in patients with plaque psoriasisNikolaos Tsamandouras, Ruolun Qiu, Jim H Hughes, et al.
Clinical Pharmacology in Drug Development|May 13, 2022
Bridging Efficacy of Tofacitinib Immediate-Release to Extended-Release Formulations for Treatment of Ulcerative Colitis: Application of a Model-Informed Drug Development ApproachArnab Mukherjee, Shinichi Tsuchiwata, Cheng Chang, et al.
Current Alzheimer Research|May 8, 2014
A multicenter, double-blind, placebo-controlled trial of the PDE9A inhibitor, PF-04447943, in Alzheimer's diseaseElias M Schwam, Timothy Nicholas, Robert Chew, et al.
CPT: Pharmacometrics & Systems Pharmacology|October 7, 2023
Dosing recommendation of nirmatrelvir/ritonavir using an integrated population pharmacokinetic analysisPhylinda L S Chan, Ravi Shankar P Singh, Donna S Cox, et al.
Clinical Pharmacology in Drug Development|May 9, 2022
Population Pharmacokinetic/Pharmacodynamic Modeling of the Effect of Abrocitinib on QT Intervals in Healthy VolunteersXiaoxing Wang, Pankaj Gupta, Bimal K Malhotra, et al.
Clinical Pharmacology and Therapeutics|April 5, 2022
Exposure-Response Characterization of Tofacitinib Efficacy in Moderate to Severe Ulcerative Colitis: Results From Phase II and Phase III Induction and Maintenance StudiesArnab Mukherjee, Shinichi Tsuchiwata, Timothy Nicholas, et al.
Molecular Genetics and Metabolism Reports|December 6, 2023
Pharmacodynamics, safety, tolerability and pharmacokinetics of a single oral dose of an engineered phenylalanine ammonia-lyase in patients with phenylketonuriaTimothy Nicholas Fazio, Louise Healy, Tim Heise, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|November 19, 2017
Estimation of Circulating Drug Metabolite Exposure in Human Using In Vitro Data and Physiologically Based Pharmacokinetic Modeling: Example of a High Metabolite/Parent Drug RatioR Scott Obach, Jian Lin, Emi Kimoto, et al.
Endocrinology, Diabetes & Metabolism Case Reports|October 12, 2018
Mitochondrial disease: an uncommon but important cause of diabetes mellitusMing Li Yee, Rosemary Wong, Mineesh Datta, et al.
Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association|September 3, 2010
Disease progression model for cognitive deterioration from Alzheimer's Disease Neuroimaging Initiative databaseKaori Ito, Brian Corrigan, Qinying Zhao, et al.
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