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Nature Cancer|August 5, 2024
Co-targeting SOS1 enhances the antitumor effects of KRASG12C inhibitors by addressing intrinsic and acquired resistanceVenu Thatikonda, Hengyu Lyu, Sabine Jurado, et al.Cancer Discovery|June 13, 2015
Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilitiesFerdinandos Skoulidis, Lauren A Byers, Lixia Diao, et al.Cell Reports|January 10, 2019
Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative PhosphorylationYuting Sun, Madhavi Bandi, Timothy Lofton, et al.Cell Metabolism|April 10, 2018
Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell TherapyTina Cascone, Jodi A McKenzie, Rina M Mbofung, et al.Nature|February 9, 2017
Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancerGiannicola Genovese, Alessandro Carugo, James Tepper, et al.Cancer Research|April 6, 2026
DPY30 is an epigenetic decoupler linking replication stress to immunoediting in pancreatic cancerFrancesca Citron, Luca Cecchetto, Elisabetta Granato, et al.Nature Communications|July 31, 2021
PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinomaVirginia Giuliani, Meredith A Miller, Chiu-Yi Liu, et al.Cancer Cell|May 13, 2015
Telomere dysfunction drives aberrant hematopoietic differentiation and myelodysplastic syndromeSimona Colla, Derrick Sek Tong Ong, Yamini Ogoti, et al.Cancer Cell|May 4, 2020
Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary CarcinomaPavlos Msaouel, Gabriel G Malouf, Xiaoping Su, et al.Nature Cancer|June 26, 2023
Interferon signaling promotes tolerance to chromosomal instability during metastatic evolution in renal cancerLuigi Perelli, Federica Carbone, Li Zhang, et al.Pageof 8