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Journal of Medicinal Chemistry|June 2, 2018
Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS SignalingJason R Abbott, Timothy R Hodges, R Nathan Daniels, et al.
Journal of Medicinal Chemistry|January 17, 2025
Discovery of Small Molecules that Bind to Son of Sevenless 2 (SOS2)Krzysztof M Zak, Alex G Waterson, Leonhard Geist, et al.
Journal of Medicinal Chemistry|September 12, 2018
Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RASTimothy R Hodges, Jason R Abbott, Andrew J Little, et al.
Journal of Medicinal Chemistry|July 25, 2025
Discovery of BI-2493, a Pan-KRAS Inhibitor Showing <i>In Vivo</i> EfficacyJoachim Bröker, Alex G Waterson, Timothy R Hodges, et al.
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