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Bioorganic & Medicinal Chemistry Letters|January 15, 2020
Orally bioavailable amine-linked macrocyclic inhibitors of factor XIaTianan Fang, James R Corte, Paul J Gilligan, et al.Bioorganic & Medicinal Chemistry|April 14, 2016
Orally bioavailable pyridine and pyrimidine-based Factor XIa inhibitors: Discovery of the methyl N-phenyl carbamate P2 prime groupJames R Corte, Tianan Fang, Donald J P Pinto, et al.Bioorganic & Medicinal Chemistry Letters|July 9, 2017
Macrocyclic inhibitors of Factor XIa: Discovery of alkyl-substituted macrocyclic amide linkers with improved potencyJames R Corte, Wu Yang, Tianan Fang, et al.Journal of Medicinal Chemistry|June 28, 2019
Discovery of Potent Protease-Activated Receptor 4 Antagonists with in Vivo Antithrombotic EfficacyMichael M Miller, Jacques Banville, Todd J Friends, et al.Journal of Medicinal Chemistry|May 17, 2002
Discovery of N-[2-[2-[[3-methoxy-4-(5-oxazolyl)phenyl]amino]-5-oxazolyl]phenyl]-N-methyl-4- morpholineacetamide as a novel and potent inhibitor of inosine monophosphate dehydrogenase with excellent in vivo activityT G Murali Dhar, Zhongqi Shen, Junqing Guo, et al.Bioorganic & Medicinal Chemistry Letters|December 26, 2015
Novel phenylalanine derived diamides as Factor XIa inhibitorsLeon M Smith, Michael J Orwat, Zilun Hu, et al.ACS Medicinal Chemistry Letters|January 8, 2019
Discovery of Clinical Candidate BMS-823778 as an Inhibitor of Human 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD-1)Jun Li, Lawrence J Kennedy, Steven J Walker, et al.Bioorganic & Medicinal Chemistry Letters|October 11, 2011
Discovery of 3-hydroxy-4-cyano-isoquinolines as novel, potent, and selective inhibitors of human 11β-hydroxydehydrogenase 1 (11β-HSD1)Shung C Wu, David Yoon, Janice Chin, et al.Journal of Medicinal Chemistry|October 28, 2017
Discovery of a Parenteral Small Molecule Coagulation Factor XIa Inhibitor Clinical Candidate (BMS-962212)Donald J P Pinto, Michael J Orwat, Leon M Smith, et al.Journal of Medicinal Chemistry|December 14, 2019
Potent, Orally Bioavailable, and Efficacious Macrocyclic Inhibitors of Factor XIa. Discovery of Pyridine-Based Macrocycles Possessing Phenylazole Carboxamide P1 GroupsJames R Corte, Donald J P Pinto, Tianan Fang, et al.Pageof 3