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Molecular Metabolism|January 29, 2022
Hypophagia induced by salmon calcitonin, but not by amylin, is partially driven by malaise and is mediated by CGRP neuronsLavinia Boccia, Tito Borner, Misgana Y Ghidewon, et al.Cell Metabolism|January 14, 2020
GDF15 Induces Anorexia through Nausea and EmesisTito Borner, Evan D Shaulson, Misgana Y Ghidewon, et al.Journal of Medicinal Chemistry|July 28, 2023
Creation of a Peptide Antagonist of the GFRAL-RET Receptor Complex for the Treatment of GDF15-Induced MalaiseTito Borner, Ian C Tinsley, Brandon T Milliken, et al.Physiology & Behavior|May 10, 2023
Screening study of anti-emetics to improve GDF15-induced malaise and anorexia: Implications for emesis controlTito Borner, Sarah A Doebley, C Daniel Furst, et al.Molecular Metabolism|May 28, 2023
GIP receptor agonism blocks chemotherapy-induced nausea and vomitingTito Borner, Benjamin C Reiner, Richard C Crist, et al.Journal of Medicinal Chemistry|January 15, 2021
Design and Evaluation of Peptide Dual-Agonists of GLP-1 and NPY2 Receptors for Glucoregulation and Weight Loss with Mitigated Nausea and EmesisBrandon T Milliken, Clinton Elfers, Oleg G Chepurny, et al.Journal of Medicinal Chemistry|March 8, 2021
Synthesis, Optimization, and Biological Evaluation of Corrinated Conjugates of the GLP-1R Agonist Exendin-4Ian C Tinsley, Tito Borner, MacKenzie L Swanson, et al.Science Translational Medicine|July 23, 2025
Hindbrain octadecaneuropeptide gliotransmission as a therapeutic target for energy balance control without nausea or emesisCaroline E Geisler, Kylie S Chichura, Oleksandr Orativskyi, et al.Diabetes, Obesity & Metabolism|December 10, 2022
Peripherally restricted oxytocin is sufficient to reduce food intake and motivation, while CNS entry is required for locomotor and taste avoidance effectsMohammed Asker, Jean-Philippe Krieger, Amber Liles, et al.Diabetes|May 2, 2022
GIPR Agonism Inhibits PYY-Induced Nausea-Like BehaviorRicardo J Samms, Richard Cosgrove, Brandy M Snider, et al.Pageof 4