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Diabetes, Obesity & Metabolism|January 13, 2018
A vitamin B12 conjugate of exendin-4 improves glucose tolerance without associated nausea or hypophagia in rodentsElizabeth G Mietlicki-Baase, Claudia G Liberini, Jayme L Workinger, et al.Cell Reports|June 20, 2020
Corrination of a GLP-1 Receptor Agonist for Glycemic Control without EmesisTito Borner, Jayme L Workinger, Ian C Tinsley, et al.Science Advances|June 18, 2025
Hypophagia and body weight loss by tirzepatide are accompanied by fewer GI adverse events compared to semaglutide in preclinical modelsTito Borner, Allison M Pataro, Sarah A Doebley, et al.Molecular Metabolism|February 12, 2026
GIPR signaling modulates PYY-induced hypophagia and malaise in rodentsTito Borner, Allison M Pataro, Genevieve R Curtis, et al.Diabetes, Obesity & Metabolism|January 9, 2026
GLP-1R biased cAMP agonism maintains glycemic control with reduced malaise and emesis in preclinical mammalian modelsCaitlin Baumer-Harrison, Danya Aldaghma, Alex D White, et al.Diabetes|August 12, 2021
GIP Receptor Agonism Attenuates GLP-1 Receptor Agonist-Induced Nausea and Emesis in Preclinical ModelsTito Borner, Caroline E Geisler, Samantha M Fortin, et al.Nature Communications|September 13, 2023
Human OPRM1 and murine Oprm1 promoter driven viral constructs for genetic access to μ-opioidergic cell typesGregory J Salimando, Sébastien Tremblay, Blake A Kimmey, et al.Pageof 4