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Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
|
April 25, 2018
New chemical tools for probing activity and inhibition of the NAD<sup>+</sup>-dependent lysine deacylase sirtuin 2
Sören Swyter, Matthias Schiedel, Daria Monaldi, et al.
Plos One
|
April 26, 2012
Lestaurtinib inhibits histone phosphorylation and androgen-dependent gene expression in prostate cancer cells
Jens Köhler, German Erlenkamp, Adrien Eberlin, et al.
Bioorganic & Medicinal Chemistry
|
June 18, 2022
Defined stereoisomers of 2″-amino NAD<sup>+</sup> and their activity against human sirtuins and a bacterial (ADP-ribosyl) transferase
Sarah Zähringer, Tobias Rumpf, Jelena Melesina, et al.
Journal of Medicinal Chemistry
|
May 3, 2011
Two-step synthesis of novel, bioactive derivatives of the ubiquitous cofactor nicotinamide adenine dinucleotide (NAD)
Thomas Pesnot, Julia Kempter, Jörg Schemies, et al.
Journal of Medicinal Chemistry
|
December 24, 2015
Aminothiazoles as Potent and Selective Sirt2 Inhibitors: A Structure-Activity Relationship Study
Matthias Schiedel, Tobias Rumpf, Berin Karaman, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Inhibitors of the NAD(+)-Dependent Protein Desuccinylase and Demalonylase Sirt5
Benjamin Maurer, Tobias Rumpf, Michael Scharfe, et al.
Journal of Medicinal Chemistry
|
December 25, 2009
Novel 3-arylideneindolin-2-ones as inhibitors of NAD+ -dependent histone deacetylases (sirtuins)
Kilian Huber, Jörg Schemies, Urszula Uciechowska, et al.
Chemmedchem
|
July 30, 2016
Identification of Highly Potent Protein Kinase C-Related Kinase 1 Inhibitors by Virtual Screening, Binding Free Energy Rescoring, and in vitro Testing
Inna Slynko, Karin Schmidtkunz, Tobias Rumpf, et al.
Journal of Molecular Biology
|
March 25, 2014
Molecular basis for the antiparasitic activity of a mercaptoacetamide derivative that inhibits histone deacetylase 8 (HDAC8) from the human pathogen schistosoma mansoni
Diana A Stolfa, Martin Marek, Julien Lancelot, et al.
Nature Communications
|
February 13, 2015
Selective Sirt2 inhibition by ligand-induced rearrangement of the active site
Tobias Rumpf, Matthias Schiedel, Berin Karaman, et al.
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Showing results (11-20 of 22) with videos related to
Sort By:
Page
of 3
Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
|
April 25, 2018
New chemical tools for probing activity and inhibition of the NAD<sup>+</sup>-dependent lysine deacylase sirtuin 2
Sören Swyter, Matthias Schiedel, Daria Monaldi, et al.
Plos One
|
April 26, 2012
Lestaurtinib inhibits histone phosphorylation and androgen-dependent gene expression in prostate cancer cells
Jens Köhler, German Erlenkamp, Adrien Eberlin, et al.
Bioorganic & Medicinal Chemistry
|
June 18, 2022
Defined stereoisomers of 2″-amino NAD<sup>+</sup> and their activity against human sirtuins and a bacterial (ADP-ribosyl) transferase
Sarah Zähringer, Tobias Rumpf, Jelena Melesina, et al.
Journal of Medicinal Chemistry
|
May 3, 2011
Two-step synthesis of novel, bioactive derivatives of the ubiquitous cofactor nicotinamide adenine dinucleotide (NAD)
Thomas Pesnot, Julia Kempter, Jörg Schemies, et al.
Journal of Medicinal Chemistry
|
December 24, 2015
Aminothiazoles as Potent and Selective Sirt2 Inhibitors: A Structure-Activity Relationship Study
Matthias Schiedel, Tobias Rumpf, Berin Karaman, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Inhibitors of the NAD(+)-Dependent Protein Desuccinylase and Demalonylase Sirt5
Benjamin Maurer, Tobias Rumpf, Michael Scharfe, et al.
Journal of Medicinal Chemistry
|
December 25, 2009
Novel 3-arylideneindolin-2-ones as inhibitors of NAD+ -dependent histone deacetylases (sirtuins)
Kilian Huber, Jörg Schemies, Urszula Uciechowska, et al.
Chemmedchem
|
July 30, 2016
Identification of Highly Potent Protein Kinase C-Related Kinase 1 Inhibitors by Virtual Screening, Binding Free Energy Rescoring, and in vitro Testing
Inna Slynko, Karin Schmidtkunz, Tobias Rumpf, et al.
Journal of Molecular Biology
|
March 25, 2014
Molecular basis for the antiparasitic activity of a mercaptoacetamide derivative that inhibits histone deacetylase 8 (HDAC8) from the human pathogen schistosoma mansoni
Diana A Stolfa, Martin Marek, Julien Lancelot, et al.
Nature Communications
|
February 13, 2015
Selective Sirt2 inhibition by ligand-induced rearrangement of the active site
Tobias Rumpf, Matthias Schiedel, Berin Karaman, et al.
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of 3