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Current Protocols in Pharmacology|February 2, 2012
In vitro muscarinic receptor radioligand-binding assaysTod Steinfeld, M Teresa Pulido-Rios, Scott Armstrong, et al.Current Protocols in Pharmacology|February 2, 2012
In vivo pharmacodynamic assays for M2 and M3 muscarinic receptorsScott Armstrong, Tod Steinfeld, M Teresa Pulido-Rios, et al.Molecular Pharmacology|December 9, 2010
THRX-198321 is a bifunctional muscarinic receptor antagonist and beta2-adrenoceptor agonist (MABA) that binds in a bimodal and multivalent mannerTod Steinfeld, Adam D Hughes, Uwe Klein, et al.Molecular Pharmacology|May 5, 2007
A novel multivalent ligand that bridges the allosteric and orthosteric binding sites of the M2 muscarinic receptorTod Steinfeld, Mathai Mammen, Jacqueline A M Smith, et al.Current Protocols in Pharmacology|February 2, 2012
In vitro isolated tissue functional muscarinic receptor assaysM Teresa Pulido-Rios, Tod Steinfeld, Scott Armstrong, et al.Pulmonary Pharmacology & Therapeutics|July 7, 2012
Preclinical efficacy of THRX-200495, a dual pharmacology muscarinic receptor antagonist and β(2)-adrenoceptor agonist (MABA)Alexander McNamara, Tod Steinfeld, Maria Teresa Pulido-Rios, et al.Naunyn-Schmiedeberg'S Archives of Pharmacology|September 28, 2011
Muscarinic receptor subtypes and signalling involved in the attenuation of isoprenaline-induced rat urinary bladder relaxationLambertus P W Witte, Noach de Haas, Mathai Mammen, et al.Bioorganic & Medicinal Chemistry Letters|February 12, 2011
Discovery of muscarinic acetylcholine receptor antagonist and beta 2 adrenoceptor agonist (MABA) dual pharmacology moleculesAdam D Hughes, Kay H Chin, Sarah L Dunham, et al.Bioorganic & Medicinal Chemistry Letters|January 19, 2016
Carbazole-containing sulfonamides and sulfamides: Discovery of cryptochrome modulators as antidiabetic agentsPaul S Humphries, Ross Bersot, John Kincaid, et al.The Journal of Pharmacology and Experimental Therapeutics|August 8, 2014
Pharmacologic characterization of GSK-961081 (TD-5959), a first-in-class inhaled bifunctional bronchodilator possessing muscarinic receptor antagonist and β2-adrenoceptor agonist propertiesSharath S Hegde, Adam D Hughes, Yan Chen, et al.Pageof 2