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Urology|November 17, 2012
Simvastatin suppresses cyclophosphamide-induced changes in urodynamics and bladder inflammationFrancis M Hughes, Paige McKeithan, Justin Ellett, et al.
Frontiers in Bioscience (Landmark Edition)|April 29, 2024
Female Type 1 Diabetic Akita Mice Demonstrate Increased Bladder Contractility via FP Receptor Activation due to NLRP3-Mediated InflammationMichael R Odom, Francis M Hughes, NiQuava Pope, et al.
BJU International|June 7, 2007
Angiotensin II plays a role in acute murine experimental autoimmune cystitisHardeep Phull, Mohamad Salkini, Todd Purves, et al.
Experimental Biology and Medicine (Maywood, N.J.)|January 19, 2022
Specialized pro-resolution mediators in the bladder: Receptor expression and recovery of bladder function from cystitisFrancis M Hughes, Armand Allkanjari, Michael R Odom, et al.
International Urology and Nephrology|August 13, 2018
Elevated hydrostatic pressure stimulates ATP release which mediates activation of the NLRP3 inflammasome via P2X4 in rat urothelial cellsCody L Dunton, J Todd Purves, Francis M Hughes, et al.
American Journal of Physiology. Renal Physiology|June 9, 2017
Bladder fibrosis during outlet obstruction is triggered through the NLRP3 inflammasome and the production of IL-1βFrancis M Hughes, Stephanie J Sexton, Huixia Jin, et al.
Life Sciences|April 5, 2022
Diabetic bladder dysfunction progresses from an overactive to an underactive phenotype in a type-1 diabetic mouse model (Akita female mouse) and is dependent on NLRP3Francis M Hughes, Armand Allkanjari, Michael R Odom, et al.
International Journal of Molecular Sciences|February 11, 2023
Why Are Some People with Lower Urinary Tract Symptoms (LUTS) Depressed? New Evidence That Peripheral Inflammation in the Bladder Causes Central Inflammation and Mood DisordersFrancis M Hughes, Michael R Odom, Anissa Cervantes, et al.
Neurourology and Urodynamics|July 20, 2024
Strict glucose control and elimination of NLRP3-induced inflammation prevents diabetic bladder dysfunction in the female Akita mouse modelFrancis M Hughes, Shelby N Harper, Huixia Jin, et al.
Continence (Amsterdam, Netherlands)|October 14, 2024
Male Akita diabetic mice develop underactive bladder independent of NLRP3 that can be prevented with blood glucose controlAustin J Livingston, J Todd Purves, Michael R Odom, et al.
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