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The Journal of Biological Chemistry|October 30, 2009
Alcadein cleavages by amyloid beta-precursor protein (APP) alpha- and gamma-secretases generate small peptides, p3-Alcs, indicating Alzheimer disease-related gamma-secretase dysfunctionSaori Hata, Sayaka Fujishige, Yoichi Araki, et al.
Neuron|September 10, 2016
Altered Cortical Dynamics and Cognitive Function upon Haploinsufficiency of the Autism-Linked Excitatory Synaptic Suppressor MDGA2Steven A Connor, Ina Ammendrup-Johnsen, Allen W Chan, et al.
Annals of Neurology|June 18, 2011
Alternative processing of γ-secretase substrates in common forms of mild cognitive impairment and Alzheimer's disease: evidence for γ-secretase dysfunctionSaori Hata, Sayaka Fujishige, Yoichi Araki, et al.
EMBO Molecular Medicine|March 30, 2023
Brain p3-Alcβ peptide restores neuronal viability impaired by Alzheimer's amyloid β-peptideSaori Hata, Haruka Saito, Takeharu Kakiuchi, et al.
Alzheimer'S & Dementia (New York, N. Y.)|November 23, 2019
Decrease in p3-Alcβ37 and p3-Alcβ40, products of Alcadein β generated by γ-secretase cleavages, in aged monkeys and patients with Alzheimer's diseaseSaori Hata, Chiori Omori, Ayano Kimura, et al.
Elife|March 26, 2024
Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairmentHideo Hagihara, Hirotaka Shoji, Satoko Hattori, et al.
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