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Therapeutic Innovation & Regulatory Science|March 25, 2026
Bioequivalence of Generic Semi-solid Topical Dermatological Drug Products: Scientific and Regulatory Perspective from Japan's 2025 GuidelinesHiroyuki Yoshida, Yasuhiro Abe, Miho Kasuga, et al.Drug Metabolism and Pharmacokinetics|January 25, 2020
pH-dependent transport kinetics of the human organic anion-transporting polypeptide 1A2Tokio Morita, Takeshi Akiyoshi, Ryo Sato, et al.Journal of Agricultural and Food Chemistry|March 1, 2022
Inhibitory Effects of Cranberry Juice and Its Components on Intestinal OATP1A2 and OATP2B1: Identification of Avicularin as a Novel InhibitorTokio Morita, Takeshi Akiyoshi, Toshiaki Tsuchitani, et al.Journal of Agricultural and Food Chemistry|November 19, 2020
Citrus Fruit-Derived Flavanone Glycoside Narirutin is a Novel Potent Inhibitor of Organic Anion-Transporting PolypeptidesTokio Morita, Takeshi Akiyoshi, Ryo Sato, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 5, 2025
Stoichiometric transport of estrone 3-sulfate among genetic variants of OATP1A2 and OATP2B1 and structural analysis by molecular dynamics simulation: Impairment of gating mechanism in the unstable inward-open conformation of OATP2B1 (Asp215Val) significantly suppress the transport activityTakeshi Akiyoshi, Arun Kumar Tonduru, Hiroki Kataoka, et al.Journal of Pharmaceutical Sciences|October 31, 2024
Kinetics of the inhibition of CYP3A4 and CYP2C19 activity by jabara juice and identification of the responsible inhibitory componentsKana Koinuma, Kenji Noto, Tokio Morita, et al.Chemical & Pharmaceutical Bulletin|January 3, 2024
Analysis of Factors Related to Variation in Dissolution Profiles Estimated from Continuously Conducted Dissolution Tests of Generic ProductsTokio Morita, Hiroyuki Yoshida, Yasuhiro Abe, et al.Pageof 2