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SLAS Discovery : Advancing Life Sciences R & D|March 15, 2026
A versatile acoustic droplet ejection mass spectrometry platform enables drug discovery for the solute carrier (SLC) target familyAnja Vogelmann, M Florian Rudolph, Yuting Wang, et al.
SLAS Technology|January 31, 2019
RapidFire BLAZE-Mode Is Boosting ESI-MS Toward High-Throughput-ScreeningTom Bretschneider, Can Ozbal, Markus Holstein, et al.
Journal of the American Chemical Society|October 23, 2013
Synthetic remodeling of the chartreusin pathway to tune antiproliferative and antibacterial activitiesNico Ueberschaar, Zhongli Xu, Kirstin Scherlach, et al.
Nature|September 20, 2013
Vinylogous chain branching catalysed by a dedicated polyketide synthase moduleTom Bretschneider, Joel B Heim, Daniel Heine, et al.
Methods in Molecular Biology (Clifton, N.J.)|October 1, 2024
Rapid Lipid Mediator Profiling by Convergence Chromatography-MS/MSGuille Metzler, Richard C King, Carmen Fernández-Metzler, et al.
ACS Medicinal Chemistry Letters|December 21, 2017
Discovery of BI-2545: A Novel Autotaxin Inhibitor That Significantly Reduces LPA Levels in VivoChristian A Kuttruff, Marco Ferrara, Tom Bretschneider, et al.
Scientific Reports|October 18, 2024
Comparative transcriptomic analysis validates iPSC derived in-vitro progressive fibrosis model as a screening tool for drug discovery and development in systemic sclerosisShyam Nathan, Yifei Wang, Matthew D'ambrosio, et al.
SLAS Discovery : Advancing Life Sciences R & D|February 22, 2018
Establishing MALDI-TOF as Versatile Drug Discovery Readout to Dissect the PTP1B Enzymatic ReactionMartin Winter, Tom Bretschneider, Carola Kleiner, et al.
Methods in Molecular Biology (Clifton, N.J.)|October 1, 2024
Prostaglandin Metabolites Analysis in Urine by LC-MS/MSGuille Metzler, Lily A Day, Richard C King, et al.
SLAS Discovery : Advancing Life Sciences R & D|May 21, 2022
Differential analyte derivatization enables unbiased MALDI-TOF-based high-throughput screening: A proof-of-concept study for the discovery of catechol-o-methyltransferase inhibitorsMartin Winter, Roman P Simon, Yuting Wang, et al.
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