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Trends in Cell Biology|January 22, 2020
RIPK1 Kinase-Dependent Death: A Symphony of Phosphorylation EventsTom Delanghe, Yves Dondelinger, Mathieu J M BertrandCell Death & Disease|November 19, 2023
NINJ1 is activated by cell swelling to regulate plasma membrane permeabilization during regulated necrosisYves Dondelinger, Dario Priem, Jon Huyghe, et al.Cell Death and Differentiation|September 1, 2025
TAB2 controls a TAK1-independent cell death checkpoint at the level of TNFR1 complex II in the TNF pathwayTom Delanghe, Mike Vadi, Annelore Haems, et al.Nature Cell Biology|September 19, 2017
MK2 phosphorylation of RIPK1 regulates TNF-mediated cell deathYves Dondelinger, Tom Delanghe, Diego Rojas-Rivera, et al.Cell Death Discovery|June 10, 2025
Primidone: a clinically promising candidate for the treatment of psoriasisTheresa Riebeling, Benedikt Kolbrink, Rebecca Philippsen, et al.Immunity|October 21, 2025
ATG9A-mediated autophagy prevents inflammatory skin disease by limiting TNFR1-driven STING activation and ZBP1-dependent cell deathDario Priem, Jon Huyghe, Barbara Gilbert, et al.Biomedicines|May 28, 2022
The Impact of RIPK1 Kinase Inhibition on Atherogenesis: A Genetic and a Pharmacological ApproachPauline Puylaert, Isabelle Coornaert, Cédric H G Neutel, et al.Nature Communications|April 10, 2020
Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammationLucie Laurien, Masahiro Nagata, Hannah Schünke, et al.Cell Death & Disease|July 15, 2021
Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitorTom Delanghe, Jon Huyghe, Seungheon Lee, et al.Nature Communications|April 17, 2019
Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammationYves Dondelinger, Tom Delanghe, Dario Priem, et al.Pageof 2