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Journal of Neuro-Oncology|August 26, 2009
Activation of PI3K/mTOR pathway occurs in most adult low-grade gliomas and predicts patient survivalSean M McBride, Daniel A Perez, Mei-Yin Polley, et al.Blood|December 3, 2003
Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesisMignon L Loh, Shashaank Vattikuti, Suzanne Schubbert, et al.The Prostate|July 17, 2015
Metabolic response of prostate cancer to nicotinamide phophoribosyltransferase inhibition in a hyperpolarized MR/PET compatible bioreactorKayvan R Keshari, David M Wilson, Mark Van Criekinge, et al.Nature Biotechnology|February 4, 2003
In situ assembly of enzyme inhibitors using extended tetheringDaniel A Erlanson, Joni W Lam, Christian Wiesmann, et al.Proceedings of the National Academy of Sciences of the United States of America|April 13, 2011
Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of tumor cellsChristy C Ong, Adrian M Jubb, Peter M Haverty, et al.Cancer Research|August 17, 2019
ERBB3 and IGF1R Signaling Are Required for Nrf2-Dependent Growth in KEAP1-Mutant Lung CancerSteffan Vartanian, James Lee, Christiaan Klijn, et al.Journal of Medicinal Chemistry|November 1, 2002
Identification of potent and selective small-molecule inhibitors of caspase-3 through the use of extended tethering and structure-based drug designIngrid C Choong, Willard Lew, Dennis Lee, et al.Nature|February 5, 2010
RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growthGeorgia Hatzivassiliou, Kyung Song, Ivana Yen, et al.Proceedings of the National Academy of Sciences of the United States of America|March 21, 2012
Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activityTill Maurer, Lindsay S Garrenton, Angela Oh, et al.Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology|December 17, 2008
Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcomaMichael D Prados, Susan M Chang, Nicholas Butowski, et al.Pageof 11