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Genome Biology|December 31, 2024
Molecular dependencies and genomic consequences of a global DNA damage tolerance defectDaniel de Groot, Aldo Spanjaard, Ronak Shah, et al.
Life Science Alliance|May 9, 2022
Genetic and compound screens uncover factors modulating cancer cell response to indisulamZiva Pogacar, Kelvin Groot, Fleur Jochems, et al.
Molecular Cell|April 13, 2021
Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balanceRuben Schep, Eva K Brinkman, Christ Leemans, et al.
Neoplasia (New York, N.Y.)|October 28, 2025
Cholesterol biosynthesis as a drug-induced vulnerability in diffuse large B cell lymphoma insensitive to EZH2 inhibitionRachele Niccolai, Camiel Göbel, Klevis Ndoj, et al.
Cancer Immunology Research|February 8, 2023
Inhibitor of Apoptosis Proteins Antagonist Induces T-cell Proliferation after Cross-Presentation by Dendritic CellsEsmée P Hoefsmit, Paula T van Royen, Disha Rao, et al.
Biorxiv : the Preprint Server for Biology|June 4, 2025
A functionally validated TCR-pMHC database for TCR specificity model developmentMarius Messemaker, Bjørn P Y Kwee, Živa Moravec, et al.
Blood|January 10, 2025
Targeting DOT1L and EZH2 synergizes in breaking the germinal center identity of diffuse large B-cell lymphomaCamiel Göbel, Rachele Niccolai, Marnix H P de Groot, et al.
Nucleic Acids Research|July 12, 2022
Division of labor within the DNA damage tolerance system reveals non-epistatic and clinically actionable targets for precision cancer medicineAldo Spanjaard, Ronak Shah, Daniël de Groot, et al.
Cell Reports. Medicine|March 20, 2024
Targeting of vulnerabilities of drug-tolerant persisters identified through functional genetics delays tumor relapseMengnuo Chen, Sara Mainardi, Cor Lieftink, et al.
Nature|October 4, 2019
Inducing and exploiting vulnerabilities for the treatment of liver cancerCun Wang, Serena Vegna, Haojie Jin, et al.
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