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Nature Medicine|January 13, 2025
Oral obeldesivir provides postexposure protection against Marburg virus in nonhuman primatesRobert W Cross, Courtney Woolsey, Abhishek N Prasad, et al.
Antiviral Research|May 7, 2022
Intravenous delivery of GS-441524 is efficacious in the African green monkey model of SARS-CoV-2 infectionJared Pitts, Darius Babusis, Meghan S Vermillion, et al.
Scientific Reports|March 7, 2017
GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and ParamyxovirusesMichael K Lo, Robert Jordan, Aaron Arvey, et al.
Antimicrobial Agents and Chemotherapy|December 7, 2007
Design and profiling of GS-9148, a novel nucleotide analog active against nucleoside-resistant variants of human immunodeficiency virus type 1, and its orally bioavailable phosphonoamidate prodrug, GS-9131Tomas Cihlar, Adrian S Ray, Constantine G Boojamra, et al.
Molecular Pharmaceutics|November 2, 2023
Lenacapavir: A Novel, Potent, and Selective First-in-Class Inhibitor of HIV-1 Capsid Function Exhibits Optimal Pharmacokinetic Properties for a Long-Acting Injectable Antiretroviral AgentRaju Subramanian, Jennifer Tang, Jim Zheng, et al.
Science Translational Medicine|April 28, 2022
Mutations in the SARS-CoV-2 RNA-dependent RNA polymerase confer resistance to remdesivir by distinct mechanismsLaura J Stevens, Andrea J Pruijssers, Hery W Lee, et al.
Bioorganic & Medicinal Chemistry|January 31, 2009
Design, synthesis, and anti-HIV activity of 4'-modified carbocyclic nucleoside phosphonate reverse transcriptase inhibitorsConstantine G Boojamra, Jay P Parrish, David Sperandio, et al.
JCI Insight|April 30, 2025
Remdesivir postexposure prophylaxis limits measles-induced "immune amnesia" and measles antibody responses in macaquesAndy Kwan Pui Chan, Liting Liu, William R Morgenlander, et al.
Science Advances|March 14, 2025
The oral drug obeldesivir protects nonhuman primates against lethal Ebola virus infectionCourtney Woolsey, Robert W Cross, Victor C Chu, et al.
Antiviral Research|January 15, 2022
Subcutaneous remdesivir administration prevents interstitial pneumonia in rhesus macaques inoculated with SARS-CoV-2Brandi N Williamson, Lizzette Pérez-Pérez, Benjamin Schwarz, et al.
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