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Journal of Medicinal Chemistry|July 17, 2024
Discovery of GS-7682, a Novel 4'-Cyano-Modified <i>C</i>-Nucleoside Prodrug with Broad Activity against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green MonkeysDustin S Siegel, Hon C Hui, Jared Pitts, et al.Nature Communications|July 11, 2025
Oral dosing of the nucleoside analog obeldesivir is efficacious against RSV infection in African green monkeysJared Pitts, J Lizbeth Reyes Zamora, Savrina Manhas, et al.The Journal of Infectious Diseases|June 10, 2021
Report of the National Institutes of Health SARS-CoV-2 Antiviral Therapeutics SummitMatthew D Hall, James M Anderson, Annaliesa Anderson, et al.Journal of Medicinal Chemistry|October 1, 2025
Discovery of Lenacapavir: First-in-Class Twice-Yearly Capsid Inhibitor for HIV-1 Treatment and Pre-exposure ProphylaxisEda Canales, Winston Tse, Scott D Schroeder, et al.Viruses|January 8, 2025
A Randomized, Blinded, Vehicle-Controlled Dose-Ranging Study to Evaluate and Characterize Remdesivir Efficacy Against Ebola Virus in Rhesus MacaquesElizabeth E Zumbrun, Carly B Garvey, Jay B Wells, et al.Nature|March 3, 2016
Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeysTravis K Warren, Robert Jordan, Michael K Lo, et al.Nature|July 3, 2020
Clinical targeting of HIV capsid protein with a long-acting small moleculeJohn O Link, Martin S Rhee, Winston C Tse, et al.Pageof 14