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Antiviral Therapy|March 15, 2014
Metabolism and antiretroviral activity of tenofovir alafenamide in CD4+ T-cells and macrophages from demographically diverse donorsRujuta A Bam, Gabriel Birkus, Darius Babusis, et al.
Antimicrobial Agents and Chemotherapy|December 25, 2013
Multiple classes of antiviral agents exhibit in vitro activity against human rhinovirus type CChris Mello, Esmeralda Aguayo, Madeleine Rodriguez, et al.
Biochemical and Biophysical Research Communications|June 23, 2004
Inhibition of the human organic anion transporter 1 by the caffeine metabolite 1-methylxanthineJens Rengelshausen, Heike Lindenmaier, Tomas Cihlar, et al.
Antimicrobial Agents and Chemotherapy|January 20, 2011
GS-8374, a novel HIV protease inhibitor, does not alter glucose homeostasis in cultured adipocytes or in a healthy-rodent model systemPaul W Hruz, Qingyun Yan, Luong Tsai, et al.
Journal of Acquired Immune Deficiency Syndromes (1999)|November 16, 2020
Simulating HIV Breakthrough and Resistance Development During Variable Adherence to Antiretroviral TreatmentAndrew Mulato, Rima Acosta, Silvia Chang, et al.
Molecular Pharmacology|April 24, 2008
Activation of 9-[(R)-2-[[(S)-[[(S)-1-(Isopropoxycarbonyl)ethyl]amino] phenoxyphosphinyl]-methoxy]propyl]adenine (GS-7340) and other tenofovir phosphonoamidate prodrugs by human proteasesGabriel Birkus, Nilima Kutty, Gong-Xin He, et al.
Journal of Virology|February 10, 2017
Toll-Like Receptor 7 Agonist GS-9620 Induces HIV Expression and HIV-Specific Immunity in Cells from HIV-Infected Individuals on Suppressive Antiretroviral TherapyAngela Tsai, Alivelu Irrinki, Jasmine Kaur, et al.
Antiviral Research|January 30, 2017
Tenofovir alafenamide (TAF) does not deplete mitochondrial DNA in human T-cell lines at intracellular concentrations exceeding clinically relevant drug exposuresKirsten M Stray, Yeojin Park, Darius Babusis, et al.
Antimicrobial Agents and Chemotherapy|April 7, 2022
Forgiveness of INSTI-Containing Regimens at Drug Concentrations Simulating Variable Adherence <i>In Vitro</i>Rima K Acosta, Michelle L D'Antoni, Andrew Mulato, et al.
Antiviral Research|February 7, 2021
Genetic conservation of SARS-CoV-2 RNA replication complex in globally circulating isolates and recently emerged variants from humans and minks suggests minimal pre-existing resistance to remdesivirRoss Martin, Jiani Li, Aiyappa Parvangada, et al.
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