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Antimicrobial Agents and Chemotherapy|April 28, 2005
Selective intracellular activation of a novel prodrug of the human immunodeficiency virus reverse transcriptase inhibitor tenofovir leads to preferential distribution and accumulation in lymphatic tissueWilliam A Lee, Gong-Xin He, Eugene Eisenberg, et al.
Antimicrobial Agents and Chemotherapy|November 13, 2008
Novel nucleotide human immunodeficiency virus reverse transcriptase inhibitor GS-9148 with a low nephrotoxic potential: characterization of renal transport and accumulationTomas Cihlar, Genevieve Laflamme, Robyn Fisher, et al.
Antimicrobial Agents and Chemotherapy|March 9, 2011
Role of cathepsin A and lysosomes in the intracellular activation of novel antipapillomavirus agent GS-9191Gabriel Birkus, Nilima Kutty, Christian R Frey, et al.
The Journal of Antimicrobial Chemotherapy|November 17, 2020
Two-dose emtricitabine/tenofovir alafenamide plus bictegravir prophylaxis protects macaques against SHIV infectionElena Bekerman, Stephanie Cox, Darius Babusis, et al.
Journal of Virology|October 26, 2012
Mutations in multiple domains of Gag drive the emergence of in vitro resistance to the phosphonate-containing HIV-1 protease inhibitor GS-8374Kirsten M Stray, Christian Callebaut, Bärbel Glass, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 18, 2001
The anti-influenza drug oseltamivir exhibits low potential to induce pharmacokinetic drug interactions via renal secretion-correlation of in vivo and in vitro studiesGeorge Hill, Tomas Cihlar, Charles Oo, et al.
Proceedings of the National Academy of Sciences of the United States of America|February 15, 2020
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infectionEmmie de Wit, Friederike Feldmann, Jacqueline Cronin, et al.
AIDS Research and Human Retroviruses|July 1, 2016
Rapid In Vitro Evaluation of Antiretroviral Barrier to Resistance at Therapeutic Drug LevelsAndrew Mulato, Derek Hansen, Alex Thielen, et al.
Elife|December 18, 2014
Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsidKe Peng, Walter Muranyi, Bärbel Glass, et al.
Antimicrobial Agents and Chemotherapy|December 6, 2006
Cathepsin A is the major hydrolase catalyzing the intracellular hydrolysis of the antiretroviral nucleotide phosphonoamidate prodrugs GS-7340 and GS-9131Gabriel Birkus, Ruth Wang, Xiaohong Liu, et al.
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