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Drug Metabolism Reviews|September 12, 2013
Nuclear receptors in regulation of biotransformation enzymes and drug transporters in the placental barrierPetr Pavek, Tomas SmutnyJournal of Pharmacological Sciences|October 25, 2014
Resveratrol as an inhibitor of pregnane X receptor (PXR): another lesson in PXR antagonismTomas Smutny, Petr PavekCurrent Drug Metabolism|December 17, 2013
Post-translational and post-transcriptional modifications of pregnane X receptor (PXR) in regulation of the cytochrome P450 superfamilyTomas Smutny, Sridhar Mani, Petr PavekDrug Metabolism Reviews|June 10, 2016
Expression of organic cation transporter 1 (OCT1): unique patterns of indirect regulation by nuclear receptors and hepatospecific gene regulationLucie Hyrsova, Tomas Smutny, Frantisek Trejtnar, et al.Journal of Clinical Medicine|May 1, 2019
Genetic Predispositions of Glucocorticoid Resistance and Therapeutic Outcomes in Polymyalgia Rheumatica and Giant Cell ArteritisTomas Smutny, Ivan Barvik, Tomas Veleta, et al.Archives of Toxicology|October 24, 2021
Expression dynamics of pregnane X receptor-controlled genes in 3D primary human hepatocyte spheroidsTomas Smutny, Veronika Bernhauerova, Lucie Smutna, et al.Toxicology Letters|January 28, 2015
Chrysin, baicalein and galangin are indirect activators of the human constitutive androstane receptor (CAR)Alejandro Carazo Fernández, Tomas Smutny, Lucie Hyrsová, et al.Biochemical Pharmacology|August 23, 2024
Rifampicin and its derivatives: stability, disposition, and affinity towards pregnane X receptor employing 2D and 3D primary human hepatocytesTomas Smutny, Lucie Smutna, Lukas Lochman, et al.Archives of Toxicology|November 9, 2020
Transcriptional and post-transcriptional regulation of the pregnane X receptor: a rationale for interindividual variability in drug metabolismTomas Smutny, Lucie Hyrsova, Albert Braeuning, et al.Basic & Clinical Pharmacology & Toxicology|March 6, 2026
Pregnane X Receptor Regulates Human Endocrine System by Inducing Sex Hormone-Binding Globulin ExpressionMaria H Ahonen, Anja Konzack, Tomas Smutny, et al.Pageof 3