Showing results (41-50 of 51) with videos related to
Sort By:
Pageof 6
Journal of Medicinal Chemistry|January 10, 2003
Competitive antagonism of AMPA receptors by ligands of different classes: crystal structure of ATPO bound to the GluR2 ligand-binding core, in comparison with DNQXAnders Hogner, Jeremy R Greenwood, Tommy Liljefors, et al.Journal of Medicinal Chemistry|May 16, 2003
Design, synthesis, and pharmacology of a highly subtype-selective GluR1/2 agonist, (RS)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid (Cl-HIBO)Esben J Bjerrum, Anders S Kristensen, Darryl S Pickering, et al.Journal of Medicinal Chemistry|May 31, 2002
Novel class of potent 4-arylalkyl substituted 3-isoxazolol GABA(A) antagonists: synthesis, pharmacology, and molecular modelingBente Frølund, Anne T Jørgensen, Lena Tagmose, et al.Journal of Medicinal Chemistry|February 14, 2008
Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotencyMads Beich-Frandsen, Darryl S Pickering, Osman Mirza, et al.Journal of Medicinal Chemistry|October 28, 2005
Total synthesis of two novel subpicomolar sarco/endoplasmatic reticulum Ca2+-ATPase inhibitors designed by an analysis of the binding site of thapsigarginHelmer Søhoel, Tommy Liljefors, Steven V Ley, et al.Journal of Medicinal Chemistry|January 22, 2005
Potent 4-aryl- or 4-arylalkyl-substituted 3-isoxazolol GABA(A) antagonists: synthesis, pharmacology, and molecular modelingBente Frølund, Lars S Jensen, Luca Guandalini, et al.Journal of Medicinal Chemistry|July 28, 2007
5-Substituted imidazole-4-acetic acid analogues: synthesis, modeling, and pharmacological characterization of a series of novel gamma-aminobutyric acid(C) receptor agonistsChristian Madsen, Anders A Jensen, Tommy Liljefors, et al.Organic & Biomolecular Chemistry|January 23, 2004
A stereochemical anomaly: the cyclised (R)-AMPA analogue (R)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridine-5-carboxylic acid [(R)-5-HPCA] resembles (S)-AMPA at glutamate receptorsStine B Vogensen, Jeremy R Greenwood, Annemarie R Varming, et al.Chemistry & Biology|November 21, 2007
Structural proof of a dimeric positive modulator bridging two identical AMPA receptor-binding sitesBirgitte H Kaae, Kasper Harpsøe, Jette S Kastrup, et al.The Journal of Biological Chemistry|June 22, 2007
Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acidHelle Hald, Peter Naur, Darryl S Pickering, et al.Pageof 6