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The Journal of Allergy and Clinical Immunology|February 13, 2021
PD-L1 on mast cells suppresses effector CD8+ T-cell activation in the skin in murine contact hypersensitivityTomoko Hirano, Tetsuya Honda, Shuto Kanameishi, et al.
Nature Communications|February 17, 2026
Phenotype of circulating tumor-reactive T cells predicts immune checkpoint inhibitor response in non-small cell lung cancerKatsuhiro Ito, Kei Iida, Tomoko Hirano, et al.
Nature Immunology|January 7, 2026
Active aldehydes accelerate CD8+ T cell exhaustion by metabolic alteration in the tumor microenvironmentYasuharu Haku, Koji Kitaoka, Koki Ichimaru, et al.
Science Translational Medicine|December 14, 2022
Combination bezafibrate and nivolumab treatment of patients with advanced non-small cell lung cancerKentaro Tanaka, Kenji Chamoto, Sho Saeki, et al.
The Journal of Clinical Investigation|April 1, 2024
Soluble immune checkpoint factors reflect exhaustion of antitumor immunity and response to PD-1 blockadeHidetoshi Hayashi, Kenji Chamoto, Ryusuke Hatae, et al.
Nature|November 4, 2021
B cell-derived GABA elicits IL-10+ macrophages to limit anti-tumour immunityBaihao Zhang, Alexis Vogelzang, Michio Miyajima, et al.
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