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Nature Chemical Biology|September 3, 2013
Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2Pallav D Patel, Pengrong Yan, Paul M Seidler, et al.
Journal of Medicinal Chemistry|February 20, 2014
Heat shock protein 70 inhibitors. 2. 2,5'-thiodipyrimidines, 5-(phenylthio)pyrimidines, 2-(pyridin-3-ylthio)pyrimidines, and 3-(phenylthio)pyridines as reversible binders to an allosteric site on heat shock protein 70Tony Taldone, Yanlong Kang, Hardik J Patel, et al.
Journal of Labelled Compounds & Radiopharmaceuticals|January 26, 2016
Radiosynthesis of the iodine-124 labeled Hsp90 inhibitor PU-H71Tony Taldone, Danuta Zatorska, Stefan O Ochiana, et al.
Cold Spring Harbor Perspectives in Biology|April 3, 2019
A Chemical Biology Approach to the Chaperome in Cancer-HSP90 and BeyondTony Taldone, Tai Wang, Anna Rodina, et al.
Blood|January 29, 2014
Improved targeting of JAK2 leads to increased therapeutic efficacy in myeloproliferative neoplasmsNeha Bhagwat, Priya Koppikar, Matthew Keller, et al.
Blood|August 15, 2013
Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignanciesUtthara Nayar, Pin Lu, Rebecca L Goldstein, et al.
Oncotarget|July 23, 2013
Posttranslational modification and conformational state of heat shock protein 90 differentially affect binding of chemically diverse small molecule inhibitorsKristin Beebe, Mehdi Mollapour, Bradley Scroggins, et al.
Stem Cell Reports|September 20, 2016
Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein AccumulationSun Young Chung, Sarah Kishinevsky, Joseph R Mazzulli, et al.
JCO Precision Oncology|December 7, 2020
Measuring Tumor Epichaperome Expression Using [124I] PU-H71 Positron Emission Tomography as a Biomarker of Response for PU-H71 Plus Nab-Paclitaxel in HER2-Negative Metastatic Breast CancerKomal L Jhaveri, Carlos H Dos Anjos, Tony Taldone, et al.
Molecular Cancer Therapeutics|June 17, 2017
Inhibition of Hsp90 Suppresses PI3K/AKT/mTOR Signaling and Has Antitumor Activity in Burkitt LymphomaLisa Giulino-Roth, Herman J van Besien, Tanner Dalton, et al.
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