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Journal of Medicinal Chemistry|April 23, 2015
Structure-activity relationship in a purine-scaffold compound series with selectivity for the endoplasmic reticulum Hsp90 paralog Grp94Hardik J Patel, Pallav D Patel, Stefan O Ochiana, et al.Proceedings of the National Academy of Sciences of the United States of America|May 7, 2009
Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer modelsEloisi Caldas-Lopes, Leandro Cerchietti, James H Ahn, et al.Cell Stem Cell|December 10, 2013
Human iPSC-based modeling of late-onset disease via progerin-induced agingJustine D Miller, Yosif M Ganat, Sarah Kishinevsky, et al.The Journal of Clinical Investigation|September 21, 2010
HSP90 is a therapeutic target in JAK2-dependent myeloproliferative neoplasms in mice and humansSachie Marubayashi, Priya Koppikar, Tony Taldone, et al.Chemistry & Biology|November 19, 2013
Identification of an allosteric pocket on human hsp70 reveals a mode of inhibition of this therapeutically important proteinAnna Rodina, Pallav D Patel, Yanlong Kang, et al.Blood|November 26, 2015
Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomasBiljana Culjkovic-Kraljacic, Tharu M Fernando, Rossella Marullo, et al.Cell Reports|December 3, 2015
A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 SpeciesHongliang Zong, Alexander Gozman, Eloisi Caldas-Lopes, et al.Cancer Research|September 4, 2021
Oncogenic HSP90 Facilitates Metabolic Alterations in Aggressive B-cell LymphomasM Nieves Calvo-Vidal, Nahuel Zamponi, Jan Krumsiek, et al.ACS Chemical Biology|June 18, 2014
Affinity purification probes of potential use to investigate the endogenous Hsp70 interactome in cancerAnna Rodina, Tony Taldone, Yanlong Kang, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|May 6, 2020
First-in-Human Trial of Epichaperome-Targeted PET in Patients with CancerMark P S Dunphy, Christina Pressl, Nagavarakishore Pillarsetty, et al.Pageof 6