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Bioorganic & Medicinal Chemistry Letters|December 8, 2005
Design and synthesis of a novel, achiral class of highly potent and selective, orally active neurokinin-1 receptor antagonistsTorsten Hoffmann, Michael Bös, Heinz Stadler, et al.
The Journal of Pharmacology and Experimental Therapeutics|April 28, 2017
Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in Mouse Models of Alzheimer's Disease-Studies on Relation to Effective Target OccupancyTorsten Hoffmann, Antje Meyer, Ulrich Heiser, et al.
Bioorganic & Medicinal Chemistry Letters|September 21, 2010
Rational design of novel pyrrolidine derivatives as orally active neurokinin-3 receptor antagonistsHassen Ratni, Theresa M Ballard, Caterina Bissantz, et al.
Peptides|January 16, 2007
Neuropeptide Y (NPY) cleaving enzymes: structural and functional homologues of dipeptidyl peptidase 4Nadine Frerker, Leona Wagner, Raik Wolf, et al.
The Journal of Biological Chemistry|February 19, 2011
Glutaminyl cyclase knock-out mice exhibit slight hypothyroidism but no hypogonadism: implications for enzyme function and drug developmentStephan Schilling, Stephanie Kohlmann, Christoph Bäuscher, et al.
Journal of Immunology (Baltimore, Md. : 1950)|July 9, 2008
Inhibition of CD26/dipeptidyl peptidase IV enhances CCL11/eotaxin-mediated recruitment of eosinophils in vivoUlf Forssmann, Carsten Stoetzer, Michael Stephan, et al.
Physiological Reports|December 5, 2013
Effects of dipeptidyl peptidase-4 inhibition in an animal model of experimental asthma: a matter of dose, route, and timeMichael Stephan, Hendrik Suhling, Jutta Schade, et al.
European Journal of Medicinal Chemistry|April 24, 2023
Neurotensin(8-13) analogs as dual NTS1 and NTS2 receptor ligands with enhanced effects on a mouse model of Parkinson's diseaseToni Kühl, Maya G Georgieva, Harald Hübner, et al.
Nature Medicine|October 7, 2008
Glutaminyl cyclase inhibition attenuates pyroglutamate Abeta and Alzheimer's disease-like pathologyStephan Schilling, Ulrike Zeitschel, Torsten Hoffmann, et al.
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