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Experimental Dermatology|November 10, 2023
Efficacy and safety of TM5614 in combination with paclitaxel in the treatment of paclitaxel-resistant cutaneous angiosarcoma: Phase II study protocolTaku Fujimura, Koji Yoshino, Motoki Nakamura, et al.Lancet (London, England)|June 4, 2013
Kidney failure: aims for the next 10 years and barriers to successGiuseppe Remuzzi, Ariela Benigni, Fredric O Finkelstein, et al.Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie|March 14, 2023
Pyridoxamine prevents increased atherosclerosis by intermittent methylglyoxal spikes in the aortic arches of ApoE<sup>-/-</sup> miceNordin M J Hanssen, Chris Tikellis, Raelene J Pickering, et al.Blood|May 11, 2012
Inhibition of PAI-1 induces neutrophil-driven neoangiogenesis and promotes tissue regeneration via production of angiocrine factors in miceYoshihiko Tashiro, Chiemi Nishida, Kaori Sato-Kusubata, et al.Science Advances|November 21, 2017
A null mutation in <i>SERPINE1</i> protects against biological aging in humansSadiya S Khan, Sanjiv J Shah, Ekaterina Klyachko, et al.Scientific Reports|January 12, 2021
Role of PAI-1 in hepatic steatosis and dyslipidemiaJoshua A Levine, Carlota Oleaga, Mesut Eren, et al.Journal of Thoracic Disease|June 17, 2024
Treatment rationale and protocol design: an investigator-initiated phase II study of combination treatment of nivolumab and TM5614, a PAI-1 inhibitor for previously treated patients with non-small cell lung cancerTakeshi Masuda, Taizo Hirata, Tomohiro Sakamoto, et al.The Journal of Clinical Investigation|September 30, 2025
Plasminogen activator inhibitor 1 promotes aortic aging-like pathophysiology in humans and miceAlireza Khoddam, Anthony Kalousdian, Mesut Eren, et al.Redox Biology|July 1, 2021
Combined glyoxalase 1 dysfunction and vitamin B6 deficiency in a schizophrenia model system causes mitochondrial dysfunction in the prefrontal cortexKazuya Toriumi, Stefano Berto, Shin Koike, et al.Diabetologia|October 29, 2013
Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetesOlaf Brouwers, Petra M G Niessen, Toshio Miyata, et al.Pageof 22