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Cancer Science|May 15, 2021
Guidelines for clinical evaluation of anti-cancer drugsHironobu Minami, Naomi Kiyota, Shiro Kimbara, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|January 21, 2012
The clinical effect of the dual-targeting strategy involving PI3K/AKT/mTOR and RAS/MEK/ERK pathways in patients with advanced cancerToshio Shimizu, Anthony W Tolcher, Kyriakos P Papadopoulos, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|February 18, 2022
Dose Escalation Data from the Phase 1 Study of the Liposomal Formulation of Eribulin (E7389-LF) in Japanese Patients with Advanced Solid TumorsJun Sato, Toshio Shimizu, Takafumi Koyama, et al.Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration|May 12, 2015
A single blind randomized controlled clinical trial of mexiletine in amyotrophic lateral sclerosis: Efficacy and safety of sodium channel blocker phase II trialKazumoto Shibuya, Sonoko Misawa, Hideki Kimura, et al.Journal of Clinical Pharmacology|January 24, 2025
Pharmacokinetic and Exposure-Response Modeling Support Body Surface Area-Based Dosing of Farletuzumab Ecteribulin in Japanese Patients with Solid TumorsSeiichi Hayato, Lora Hamuro, Toshio Shimizu, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|January 14, 2021
Safety and Immunogenicity of LY3415244, a Bispecific Antibody Against TIM-3 and PD-L1, in Patients With Advanced Solid TumorsMatthew D Hellmann, Nicoletta Bivi, Boris Calderon, et al.Cancer Discovery|June 27, 2023
Clinical Activity and Exploratory Resistance Mechanism of Milademetan, an MDM2 Inhibitor, in Intimal Sarcoma with MDM2 Amplification: An Open-Label Phase Ib/II StudyTakafumi Koyama, Toshio Shimizu, Yuki Kojima, et al.Molecular Therapy. Oncology|June 29, 2026
AGTR1 signaling contributes to tumor immunity and therapy response in non-small cell lung cancerTatsuki Ikoma, Keigo Araki, Mai Kitagawa, et al.Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases|May 29, 2012
Reduction rate of body mass index predicts prognosis for survival in amyotrophic lateral sclerosis: a multicenter study in JapanToshio Shimizu, Utako Nagaoka, Yuki Nakayama, et al.Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology|June 16, 2023
First-in-Human, Phase I Dose-Escalation and Dose-Expansion Study of Trophoblast Cell-Surface Antigen 2-Directed Antibody-Drug Conjugate Datopotamab Deruxtecan in Non-Small-Cell Lung Cancer: TROPION-PanTumor01Toshio Shimizu, Jacob Sands, Kiyotaka Yoh, et al.Pageof 22