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ACS Chemical Neuroscience
|
March 2, 2021
Harnessing Preclinical Data as a Predictive Tool for Human Brain Tissue Targeting
Nandini C Patel, Bo Feng, Xinjun Hou, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
|
November 18, 2011
Csnk1e is a genetic regulator of sensitivity to psychostimulants and opioids
Camron D Bryant, Clarissa C Parker, Lili Zhou, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
January 27, 2019
In Vitro-In Vivo Extrapolation of Key Transporter Activity at the Blood-Brain Barrier
Patrick E Trapa, Matthew D Troutman, Thomas Y Lau, et al.
Scientific Reports
|
April 11, 2019
Author Correction: Dopamine D3 receptor antagonist reveals a cryptic pocket in aminergic GPCRs
Noelia Ferruz, Stefan Doerr, Michelle A Vanase-Frawley, et al.
Scientific Reports
|
January 19, 2018
Dopamine D3 receptor antagonist reveals a cryptic pocket in aminergic GPCRs
Noelia Ferruz, Stefan Doerr, Michelle A Vanase-Frawley, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 13, 2014
Kinase domain inhibition of leucine rich repeat kinase 2 (LRRK2) using a [1,2,4]triazolo[4,3-b]pyridazine scaffold
Paul Galatsis, Jaclyn L Henderson, Bethany L Kormos, et al.
ACS Chemical Neuroscience
|
June 14, 2017
Identification and Profiling of a Selective and Brain Penetrant Radioligand for in Vivo Target Occupancy Measurement of Casein Kinase 1 (CK1) Inhibitors
Travis T Wager, Paul Galatsis, Ramalakshmi Y Chandrasekaran, et al.
ACS Chemical Neuroscience
|
October 10, 2014
Casein kinase 1δ/ε inhibitor PF-5006739 attenuates opioid drug-seeking behavior
Travis T Wager, Ramalakshmi Y Chandrasekaran, Jenifer Bradley, et al.
Journal of Medicinal Chemistry
|
May 9, 2013
Design and selection parameters to accelerate the discovery of novel central nervous system positron emission tomography (PET) ligands and their application in the development of a novel phosphodiesterase 2A PET ligand
Lei Zhang, Anabella Villalobos, Elizabeth M Beck, et al.
Journal of Medicinal Chemistry
|
October 30, 2014
Discovery and preclinical profiling of 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor
Jaclyn L Henderson, Bethany L Kormos, Matthew M Hayward, et al.
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Search research articles
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Showing results (11-20 of 27) with videos related to
Sort By:
Page
of 3
ACS Chemical Neuroscience
|
March 2, 2021
Harnessing Preclinical Data as a Predictive Tool for Human Brain Tissue Targeting
Nandini C Patel, Bo Feng, Xinjun Hou, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
|
November 18, 2011
Csnk1e is a genetic regulator of sensitivity to psychostimulants and opioids
Camron D Bryant, Clarissa C Parker, Lili Zhou, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
January 27, 2019
In Vitro-In Vivo Extrapolation of Key Transporter Activity at the Blood-Brain Barrier
Patrick E Trapa, Matthew D Troutman, Thomas Y Lau, et al.
Scientific Reports
|
April 11, 2019
Author Correction: Dopamine D3 receptor antagonist reveals a cryptic pocket in aminergic GPCRs
Noelia Ferruz, Stefan Doerr, Michelle A Vanase-Frawley, et al.
Scientific Reports
|
January 19, 2018
Dopamine D3 receptor antagonist reveals a cryptic pocket in aminergic GPCRs
Noelia Ferruz, Stefan Doerr, Michelle A Vanase-Frawley, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 13, 2014
Kinase domain inhibition of leucine rich repeat kinase 2 (LRRK2) using a [1,2,4]triazolo[4,3-b]pyridazine scaffold
Paul Galatsis, Jaclyn L Henderson, Bethany L Kormos, et al.
ACS Chemical Neuroscience
|
June 14, 2017
Identification and Profiling of a Selective and Brain Penetrant Radioligand for in Vivo Target Occupancy Measurement of Casein Kinase 1 (CK1) Inhibitors
Travis T Wager, Paul Galatsis, Ramalakshmi Y Chandrasekaran, et al.
ACS Chemical Neuroscience
|
October 10, 2014
Casein kinase 1δ/ε inhibitor PF-5006739 attenuates opioid drug-seeking behavior
Travis T Wager, Ramalakshmi Y Chandrasekaran, Jenifer Bradley, et al.
Journal of Medicinal Chemistry
|
May 9, 2013
Design and selection parameters to accelerate the discovery of novel central nervous system positron emission tomography (PET) ligands and their application in the development of a novel phosphodiesterase 2A PET ligand
Lei Zhang, Anabella Villalobos, Elizabeth M Beck, et al.
Journal of Medicinal Chemistry
|
October 30, 2014
Discovery and preclinical profiling of 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor
Jaclyn L Henderson, Bethany L Kormos, Matthew M Hayward, et al.
Page
of 3